Bacterial/viral filtration : Let the breather beware
Most clinicians believe that any device that is marketed as a "bacterial/viral filter" must necessarily be capable of capturing any individual bacteria or viruses that might be suspended within inhaled or exhaled gases. We were surprised to discover that this is, by no means, a justifiable...
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Veröffentlicht in: | Chest 2001-10, Vol.120 (4), p.1377-1389 |
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description | Most clinicians believe that any device that is marketed as a "bacterial/viral filter" must necessarily be capable of capturing any individual bacteria or viruses that might be suspended within inhaled or exhaled gases. We were surprised to discover that this is, by no means, a justifiable assumption. This article describes testing methods that manufacturers employ to generate the often-misleading efficiency specifications that are claimed for some of these devices. We discuss articles that have documented the presence of airborne pathogens in the effluent of a ventilator circuit, and characterize the attributes that a competent filter must exhibit if it is to succeed in protecting patients and caregivers from incidental exposure to bacteria, viruses, aerosolized drugs, and endotoxins. This article continues with a discussion of the numbers of particles that are commonly produced with commercially available pneumatic nebulizers, the comparative performance characteristics of filters and heat/moisture exchanging filters (HMEFs), and the success or failure of various brands of HMEFs to comply with the guidelines recently developed by the Centers for Disease Control and Prevention for the management of patients who are harboring active tuberculosis. The presentation concludes with a description of the standards that apply to any filter that classifies as a high-efficiency particulate aerosol (HEPA) device, and demonstrates that the performance of filters/HMEFs in common clinical use can range from approximately 1/50th to > 30-fold the efficiency of a HEPA-grade device. Those who frequent the bedside of patients receiving ventilation might unwittingly be placing themselves at considerable risk of exposure to infectious microaerosols, but methods are available to dramatically decrease those risks. |
doi_str_mv | 10.1378/chest.120.4.1377 |
format | Article |
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We were surprised to discover that this is, by no means, a justifiable assumption. This article describes testing methods that manufacturers employ to generate the often-misleading efficiency specifications that are claimed for some of these devices. We discuss articles that have documented the presence of airborne pathogens in the effluent of a ventilator circuit, and characterize the attributes that a competent filter must exhibit if it is to succeed in protecting patients and caregivers from incidental exposure to bacteria, viruses, aerosolized drugs, and endotoxins. This article continues with a discussion of the numbers of particles that are commonly produced with commercially available pneumatic nebulizers, the comparative performance characteristics of filters and heat/moisture exchanging filters (HMEFs), and the success or failure of various brands of HMEFs to comply with the guidelines recently developed by the Centers for Disease Control and Prevention for the management of patients who are harboring active tuberculosis. The presentation concludes with a description of the standards that apply to any filter that classifies as a high-efficiency particulate aerosol (HEPA) device, and demonstrates that the performance of filters/HMEFs in common clinical use can range from approximately 1/50th to > 30-fold the efficiency of a HEPA-grade device. 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We were surprised to discover that this is, by no means, a justifiable assumption. This article describes testing methods that manufacturers employ to generate the often-misleading efficiency specifications that are claimed for some of these devices. We discuss articles that have documented the presence of airborne pathogens in the effluent of a ventilator circuit, and characterize the attributes that a competent filter must exhibit if it is to succeed in protecting patients and caregivers from incidental exposure to bacteria, viruses, aerosolized drugs, and endotoxins. This article continues with a discussion of the numbers of particles that are commonly produced with commercially available pneumatic nebulizers, the comparative performance characteristics of filters and heat/moisture exchanging filters (HMEFs), and the success or failure of various brands of HMEFs to comply with the guidelines recently developed by the Centers for Disease Control and Prevention for the management of patients who are harboring active tuberculosis. The presentation concludes with a description of the standards that apply to any filter that classifies as a high-efficiency particulate aerosol (HEPA) device, and demonstrates that the performance of filters/HMEFs in common clinical use can range from approximately 1/50th to > 30-fold the efficiency of a HEPA-grade device. Those who frequent the bedside of patients receiving ventilation might unwittingly be placing themselves at considerable risk of exposure to infectious microaerosols, but methods are available to dramatically decrease those risks.</description><subject>Aerosols</subject><subject>Air Microbiology</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Aqueous solutions</subject><subject>Bacteria</subject><subject>Biological and medical sciences</subject><subject>Ceramic fibers</subject><subject>Disease control</subject><subject>Efficiency</subject><subject>Emergency and intensive respiratory care</subject><subject>Equipment Design</subject><subject>Filtration - instrumentation</subject><subject>Gases</subject><subject>Humans</subject><subject>Intensive care medicine</subject><subject>Medical sciences</subject><subject>Microscopy, Electron, Scanning</subject><subject>Nebulizers and Vaporizers</subject><subject>Particle Size</subject><subject>Pediatrics</subject><subject>Respiratory Protective Devices - microbiology</subject><subject>Tuberculosis</subject><subject>Ventilators</subject><subject>Ventilators, Mechanical</subject><subject>Viruses</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkM1LxDAQxYMo7rp69yRF0Fu7mSRtUm-6-AULXvRc0nTCZum2a9Iq_vdmcUXw9JjhN2_eDCHnQDPgUs3NCsOQAaOZ2DXkAZlCySHlueCHZEopsJQXJZuQkxDWNNZQFsdkApCXkCsxJeJOmwG90-38w3ndJta1g9eD67vkJlnikAwrTGqPOqpPavzUHk_JkdVtwLO9zsjbw_3r4ildvjw-L26X6ZYVYkhlwzFvqAWbM8VLoAyk5g1wXtYMJc-LRkpeYIPWWmWVqAHioFKGW6Ms4zNy_eO79f37GE-tNi4YbFvdYT-GSjJQBQMawct_4LoffRezVYxSEZewIkIXe2isN9hUW-822n9Vv8-IwNUe0MHo1nrdGRf-OEGl2hl9A0kmbCo</recordid><startdate>20011001</startdate><enddate>20011001</enddate><creator>DEMERS, Robert R</creator><general>American College of Chest Physicians</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20011001</creationdate><title>Bacterial/viral filtration : Let the breather beware</title><author>DEMERS, Robert R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p264t-7d3e5d0f1f5283910217a3d1339b2e7356d7736edefff8f84b1126488c3fc8f23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Aerosols</topic><topic>Air Microbiology</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Aqueous solutions</topic><topic>Bacteria</topic><topic>Biological and medical sciences</topic><topic>Ceramic fibers</topic><topic>Disease control</topic><topic>Efficiency</topic><topic>Emergency and intensive respiratory care</topic><topic>Equipment Design</topic><topic>Filtration - instrumentation</topic><topic>Gases</topic><topic>Humans</topic><topic>Intensive care medicine</topic><topic>Medical sciences</topic><topic>Microscopy, Electron, Scanning</topic><topic>Nebulizers and Vaporizers</topic><topic>Particle Size</topic><topic>Pediatrics</topic><topic>Respiratory Protective Devices - microbiology</topic><topic>Tuberculosis</topic><topic>Ventilators</topic><topic>Ventilators, Mechanical</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DEMERS, Robert R</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DEMERS, Robert R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bacterial/viral filtration : Let the breather beware</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>2001-10-01</date><risdate>2001</risdate><volume>120</volume><issue>4</issue><spage>1377</spage><epage>1389</epage><pages>1377-1389</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><coden>CHETBF</coden><abstract>Most clinicians believe that any device that is marketed as a "bacterial/viral filter" must necessarily be capable of capturing any individual bacteria or viruses that might be suspended within inhaled or exhaled gases. We were surprised to discover that this is, by no means, a justifiable assumption. This article describes testing methods that manufacturers employ to generate the often-misleading efficiency specifications that are claimed for some of these devices. We discuss articles that have documented the presence of airborne pathogens in the effluent of a ventilator circuit, and characterize the attributes that a competent filter must exhibit if it is to succeed in protecting patients and caregivers from incidental exposure to bacteria, viruses, aerosolized drugs, and endotoxins. This article continues with a discussion of the numbers of particles that are commonly produced with commercially available pneumatic nebulizers, the comparative performance characteristics of filters and heat/moisture exchanging filters (HMEFs), and the success or failure of various brands of HMEFs to comply with the guidelines recently developed by the Centers for Disease Control and Prevention for the management of patients who are harboring active tuberculosis. The presentation concludes with a description of the standards that apply to any filter that classifies as a high-efficiency particulate aerosol (HEPA) device, and demonstrates that the performance of filters/HMEFs in common clinical use can range from approximately 1/50th to > 30-fold the efficiency of a HEPA-grade device. Those who frequent the bedside of patients receiving ventilation might unwittingly be placing themselves at considerable risk of exposure to infectious microaerosols, but methods are available to dramatically decrease those risks.</abstract><cop>Northbrook, IL</cop><pub>American College of Chest Physicians</pub><pmid>11591584</pmid><doi>10.1378/chest.120.4.1377</doi><tpages>13</tpages></addata></record> |
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subjects | Aerosols Air Microbiology Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Aqueous solutions Bacteria Biological and medical sciences Ceramic fibers Disease control Efficiency Emergency and intensive respiratory care Equipment Design Filtration - instrumentation Gases Humans Intensive care medicine Medical sciences Microscopy, Electron, Scanning Nebulizers and Vaporizers Particle Size Pediatrics Respiratory Protective Devices - microbiology Tuberculosis Ventilators Ventilators, Mechanical Viruses |
title | Bacterial/viral filtration : Let the breather beware |
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