Bacterial/viral filtration : Let the breather beware

Most clinicians believe that any device that is marketed as a "bacterial/viral filter" must necessarily be capable of capturing any individual bacteria or viruses that might be suspended within inhaled or exhaled gases. We were surprised to discover that this is, by no means, a justifiable...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chest 2001-10, Vol.120 (4), p.1377-1389
1. Verfasser: DEMERS, Robert R
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1389
container_issue 4
container_start_page 1377
container_title Chest
container_volume 120
creator DEMERS, Robert R
description Most clinicians believe that any device that is marketed as a "bacterial/viral filter" must necessarily be capable of capturing any individual bacteria or viruses that might be suspended within inhaled or exhaled gases. We were surprised to discover that this is, by no means, a justifiable assumption. This article describes testing methods that manufacturers employ to generate the often-misleading efficiency specifications that are claimed for some of these devices. We discuss articles that have documented the presence of airborne pathogens in the effluent of a ventilator circuit, and characterize the attributes that a competent filter must exhibit if it is to succeed in protecting patients and caregivers from incidental exposure to bacteria, viruses, aerosolized drugs, and endotoxins. This article continues with a discussion of the numbers of particles that are commonly produced with commercially available pneumatic nebulizers, the comparative performance characteristics of filters and heat/moisture exchanging filters (HMEFs), and the success or failure of various brands of HMEFs to comply with the guidelines recently developed by the Centers for Disease Control and Prevention for the management of patients who are harboring active tuberculosis. The presentation concludes with a description of the standards that apply to any filter that classifies as a high-efficiency particulate aerosol (HEPA) device, and demonstrates that the performance of filters/HMEFs in common clinical use can range from approximately 1/50th to > 30-fold the efficiency of a HEPA-grade device. Those who frequent the bedside of patients receiving ventilation might unwittingly be placing themselves at considerable risk of exposure to infectious microaerosols, but methods are available to dramatically decrease those risks.
doi_str_mv 10.1378/chest.120.4.1377
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_72186210</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>87426768</sourcerecordid><originalsourceid>FETCH-LOGICAL-p264t-7d3e5d0f1f5283910217a3d1339b2e7356d7736edefff8f84b1126488c3fc8f23</originalsourceid><addsrcrecordid>eNpdkM1LxDAQxYMo7rp69yRF0Fu7mSRtUm-6-AULXvRc0nTCZum2a9Iq_vdmcUXw9JjhN2_eDCHnQDPgUs3NCsOQAaOZ2DXkAZlCySHlueCHZEopsJQXJZuQkxDWNNZQFsdkApCXkCsxJeJOmwG90-38w3ndJta1g9eD67vkJlnikAwrTGqPOqpPavzUHk_JkdVtwLO9zsjbw_3r4ildvjw-L26X6ZYVYkhlwzFvqAWbM8VLoAyk5g1wXtYMJc-LRkpeYIPWWmWVqAHioFKGW6Ms4zNy_eO79f37GE-tNi4YbFvdYT-GSjJQBQMawct_4LoffRezVYxSEZewIkIXe2isN9hUW-822n9Vv8-IwNUe0MHo1nrdGRf-OEGl2hl9A0kmbCo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>200473626</pqid></control><display><type>article</type><title>Bacterial/viral filtration : Let the breather beware</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>DEMERS, Robert R</creator><creatorcontrib>DEMERS, Robert R</creatorcontrib><description>Most clinicians believe that any device that is marketed as a "bacterial/viral filter" must necessarily be capable of capturing any individual bacteria or viruses that might be suspended within inhaled or exhaled gases. We were surprised to discover that this is, by no means, a justifiable assumption. This article describes testing methods that manufacturers employ to generate the often-misleading efficiency specifications that are claimed for some of these devices. We discuss articles that have documented the presence of airborne pathogens in the effluent of a ventilator circuit, and characterize the attributes that a competent filter must exhibit if it is to succeed in protecting patients and caregivers from incidental exposure to bacteria, viruses, aerosolized drugs, and endotoxins. This article continues with a discussion of the numbers of particles that are commonly produced with commercially available pneumatic nebulizers, the comparative performance characteristics of filters and heat/moisture exchanging filters (HMEFs), and the success or failure of various brands of HMEFs to comply with the guidelines recently developed by the Centers for Disease Control and Prevention for the management of patients who are harboring active tuberculosis. The presentation concludes with a description of the standards that apply to any filter that classifies as a high-efficiency particulate aerosol (HEPA) device, and demonstrates that the performance of filters/HMEFs in common clinical use can range from approximately 1/50th to &gt; 30-fold the efficiency of a HEPA-grade device. Those who frequent the bedside of patients receiving ventilation might unwittingly be placing themselves at considerable risk of exposure to infectious microaerosols, but methods are available to dramatically decrease those risks.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.120.4.1377</identifier><identifier>PMID: 11591584</identifier><identifier>CODEN: CHETBF</identifier><language>eng</language><publisher>Northbrook, IL: American College of Chest Physicians</publisher><subject>Aerosols ; Air Microbiology ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Aqueous solutions ; Bacteria ; Biological and medical sciences ; Ceramic fibers ; Disease control ; Efficiency ; Emergency and intensive respiratory care ; Equipment Design ; Filtration - instrumentation ; Gases ; Humans ; Intensive care medicine ; Medical sciences ; Microscopy, Electron, Scanning ; Nebulizers and Vaporizers ; Particle Size ; Pediatrics ; Respiratory Protective Devices - microbiology ; Tuberculosis ; Ventilators ; Ventilators, Mechanical ; Viruses</subject><ispartof>Chest, 2001-10, Vol.120 (4), p.1377-1389</ispartof><rights>2002 INIST-CNRS</rights><rights>Copyright American College of Chest Physicians Oct 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=14078626$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11591584$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DEMERS, Robert R</creatorcontrib><title>Bacterial/viral filtration : Let the breather beware</title><title>Chest</title><addtitle>Chest</addtitle><description>Most clinicians believe that any device that is marketed as a "bacterial/viral filter" must necessarily be capable of capturing any individual bacteria or viruses that might be suspended within inhaled or exhaled gases. We were surprised to discover that this is, by no means, a justifiable assumption. This article describes testing methods that manufacturers employ to generate the often-misleading efficiency specifications that are claimed for some of these devices. We discuss articles that have documented the presence of airborne pathogens in the effluent of a ventilator circuit, and characterize the attributes that a competent filter must exhibit if it is to succeed in protecting patients and caregivers from incidental exposure to bacteria, viruses, aerosolized drugs, and endotoxins. This article continues with a discussion of the numbers of particles that are commonly produced with commercially available pneumatic nebulizers, the comparative performance characteristics of filters and heat/moisture exchanging filters (HMEFs), and the success or failure of various brands of HMEFs to comply with the guidelines recently developed by the Centers for Disease Control and Prevention for the management of patients who are harboring active tuberculosis. The presentation concludes with a description of the standards that apply to any filter that classifies as a high-efficiency particulate aerosol (HEPA) device, and demonstrates that the performance of filters/HMEFs in common clinical use can range from approximately 1/50th to &gt; 30-fold the efficiency of a HEPA-grade device. Those who frequent the bedside of patients receiving ventilation might unwittingly be placing themselves at considerable risk of exposure to infectious microaerosols, but methods are available to dramatically decrease those risks.</description><subject>Aerosols</subject><subject>Air Microbiology</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Aqueous solutions</subject><subject>Bacteria</subject><subject>Biological and medical sciences</subject><subject>Ceramic fibers</subject><subject>Disease control</subject><subject>Efficiency</subject><subject>Emergency and intensive respiratory care</subject><subject>Equipment Design</subject><subject>Filtration - instrumentation</subject><subject>Gases</subject><subject>Humans</subject><subject>Intensive care medicine</subject><subject>Medical sciences</subject><subject>Microscopy, Electron, Scanning</subject><subject>Nebulizers and Vaporizers</subject><subject>Particle Size</subject><subject>Pediatrics</subject><subject>Respiratory Protective Devices - microbiology</subject><subject>Tuberculosis</subject><subject>Ventilators</subject><subject>Ventilators, Mechanical</subject><subject>Viruses</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkM1LxDAQxYMo7rp69yRF0Fu7mSRtUm-6-AULXvRc0nTCZum2a9Iq_vdmcUXw9JjhN2_eDCHnQDPgUs3NCsOQAaOZ2DXkAZlCySHlueCHZEopsJQXJZuQkxDWNNZQFsdkApCXkCsxJeJOmwG90-38w3ndJta1g9eD67vkJlnikAwrTGqPOqpPavzUHk_JkdVtwLO9zsjbw_3r4ildvjw-L26X6ZYVYkhlwzFvqAWbM8VLoAyk5g1wXtYMJc-LRkpeYIPWWmWVqAHioFKGW6Ms4zNy_eO79f37GE-tNi4YbFvdYT-GSjJQBQMawct_4LoffRezVYxSEZewIkIXe2isN9hUW-822n9Vv8-IwNUe0MHo1nrdGRf-OEGl2hl9A0kmbCo</recordid><startdate>20011001</startdate><enddate>20011001</enddate><creator>DEMERS, Robert R</creator><general>American College of Chest Physicians</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20011001</creationdate><title>Bacterial/viral filtration : Let the breather beware</title><author>DEMERS, Robert R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p264t-7d3e5d0f1f5283910217a3d1339b2e7356d7736edefff8f84b1126488c3fc8f23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Aerosols</topic><topic>Air Microbiology</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Aqueous solutions</topic><topic>Bacteria</topic><topic>Biological and medical sciences</topic><topic>Ceramic fibers</topic><topic>Disease control</topic><topic>Efficiency</topic><topic>Emergency and intensive respiratory care</topic><topic>Equipment Design</topic><topic>Filtration - instrumentation</topic><topic>Gases</topic><topic>Humans</topic><topic>Intensive care medicine</topic><topic>Medical sciences</topic><topic>Microscopy, Electron, Scanning</topic><topic>Nebulizers and Vaporizers</topic><topic>Particle Size</topic><topic>Pediatrics</topic><topic>Respiratory Protective Devices - microbiology</topic><topic>Tuberculosis</topic><topic>Ventilators</topic><topic>Ventilators, Mechanical</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DEMERS, Robert R</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DEMERS, Robert R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bacterial/viral filtration : Let the breather beware</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>2001-10-01</date><risdate>2001</risdate><volume>120</volume><issue>4</issue><spage>1377</spage><epage>1389</epage><pages>1377-1389</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><coden>CHETBF</coden><abstract>Most clinicians believe that any device that is marketed as a "bacterial/viral filter" must necessarily be capable of capturing any individual bacteria or viruses that might be suspended within inhaled or exhaled gases. We were surprised to discover that this is, by no means, a justifiable assumption. This article describes testing methods that manufacturers employ to generate the often-misleading efficiency specifications that are claimed for some of these devices. We discuss articles that have documented the presence of airborne pathogens in the effluent of a ventilator circuit, and characterize the attributes that a competent filter must exhibit if it is to succeed in protecting patients and caregivers from incidental exposure to bacteria, viruses, aerosolized drugs, and endotoxins. This article continues with a discussion of the numbers of particles that are commonly produced with commercially available pneumatic nebulizers, the comparative performance characteristics of filters and heat/moisture exchanging filters (HMEFs), and the success or failure of various brands of HMEFs to comply with the guidelines recently developed by the Centers for Disease Control and Prevention for the management of patients who are harboring active tuberculosis. The presentation concludes with a description of the standards that apply to any filter that classifies as a high-efficiency particulate aerosol (HEPA) device, and demonstrates that the performance of filters/HMEFs in common clinical use can range from approximately 1/50th to &gt; 30-fold the efficiency of a HEPA-grade device. Those who frequent the bedside of patients receiving ventilation might unwittingly be placing themselves at considerable risk of exposure to infectious microaerosols, but methods are available to dramatically decrease those risks.</abstract><cop>Northbrook, IL</cop><pub>American College of Chest Physicians</pub><pmid>11591584</pmid><doi>10.1378/chest.120.4.1377</doi><tpages>13</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0012-3692
ispartof Chest, 2001-10, Vol.120 (4), p.1377-1389
issn 0012-3692
1931-3543
language eng
recordid cdi_proquest_miscellaneous_72186210
source MEDLINE; Alma/SFX Local Collection
subjects Aerosols
Air Microbiology
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Aqueous solutions
Bacteria
Biological and medical sciences
Ceramic fibers
Disease control
Efficiency
Emergency and intensive respiratory care
Equipment Design
Filtration - instrumentation
Gases
Humans
Intensive care medicine
Medical sciences
Microscopy, Electron, Scanning
Nebulizers and Vaporizers
Particle Size
Pediatrics
Respiratory Protective Devices - microbiology
Tuberculosis
Ventilators
Ventilators, Mechanical
Viruses
title Bacterial/viral filtration : Let the breather beware
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T13%3A19%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Bacterial/viral%20filtration%20:%20Let%20the%20breather%20beware&rft.jtitle=Chest&rft.au=DEMERS,%20Robert%20R&rft.date=2001-10-01&rft.volume=120&rft.issue=4&rft.spage=1377&rft.epage=1389&rft.pages=1377-1389&rft.issn=0012-3692&rft.eissn=1931-3543&rft.coden=CHETBF&rft_id=info:doi/10.1378/chest.120.4.1377&rft_dat=%3Cproquest_pubme%3E87426768%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=200473626&rft_id=info:pmid/11591584&rfr_iscdi=true