Mechanisms modulating estrogen-induced uterine vasodilation

Estrogen, a potent vasodilator, has its greatest effects in reproductive tissues, e.g., increasing uterine blood flow (UBF) 5- to 10-fold within 90 min after a bolus dose. High-conductance potassium channels and nitric oxide (NO) contribute to the uterine responses, but other factors may be involved...

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Veröffentlicht in:	Vascular pharmacology 2002-02, Vol.38 (2), p.115-125
Hauptverfasser:	Rosenfeld, Charles R, Roy, Timothy, Cox, Blair E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dose-Response Relationship, Drug Estrogens - pharmacology Estrogens - physiology Female Nitric oxide Potassium channels Sheep Uterine blood flow Uterus - blood supply Uterus - drug effects Uterus - physiology Vasodilation - drug effects Vasodilation - physiology
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