Differential Properties of Mucous Glycoproteins in Rat Nasal Epithelium . A Comparison between Allergic Inflammation and Lipopolysaccharide Stimulation

To examine the differential properties of mucous glycoproteins, we produced hypertrophic and metaplastic changes in goblet cells of rat nasal epithelium by intranasal instillation of ovalbumin (OVA) in OVA-sensitized rats, and by intranasal lipopolysaccharide (LPS) instillation. The epithelial mucos...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2001-09, Vol.164 (6), p.1077-1082
Hauptverfasser:	SHIMIZU, TAKESHI, HIRANO, HITOMI, SHIMIZU, SHINO, KISHIOKA, CHIKAKO, SAKAKURA, YASUO, MAJIMA, YUICHI
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Data Interpretation, Statistical Epithelium - metabolism Epithelium - pathology Epithelium - physiology Goblet Cells - metabolism Goblet Cells - pathology Goblet Cells - physiology Histocytochemistry Hypersensitivity - pathology Hypersensitivity - physiopathology Inflammation - pathology Inflammation - physiopathology Lectins Lipopolysaccharides - administration & dosage Male Medical sciences Mucins - genetics Mucins - metabolism Mucins - physiology Mucus - metabolism Mucus - physiology Ovalbumin - administration & dosage Pneumology Rats Rats, Inbred F344 Respiratory system : syndromes and miscellaneous diseases Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Sodium Chloride - administration & dosage
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