Selectivity of the .beta.-adrenergic receptor among Gs, Gi's, and Go: assay using recombinant .alpha. subunits in reconstituted phospholipid vesicles

The selective regulation of Gs (long and short forms), Gi's (1, 2, and 3), and Go by the beta-adrenergic receptor was assessed quantitatively after coreconstitution of purified receptor, purified G-protein beta gamma subunits, and individual recombinant G-protein alpha subunits that were expres...

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Veröffentlicht in:	Biochemistry (Easton) 1991-11, Vol.30 (44), p.10769-10777
Hauptverfasser:	Rubenstein, Ronald C, Linder, Maurine E, Ross, Elliott M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain Chemistry Cattle Cell receptors Cell structures and functions Dithiothreitol - pharmacology Erythrocytes - chemistry Escherichia coli - metabolism Fundamental and applied biological sciences. Psychology GTP Phosphohydrolases - metabolism GTP-Binding Proteins - metabolism Guanosine 5'-O-(3-Thiotriphosphate) - metabolism Guanosine Diphosphate - metabolism Kinetics Liposomes - metabolism Macromolecular Substances Molecular and cellular biology Monoamines receptors (catecholamine, serotonine, histamine, acetylcholine) Phospholipids - metabolism Receptors, Adrenergic, beta - metabolism Recombinant Proteins - metabolism Turkeys - blood
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