N-methyl-D-aspartate receptors mediate dopamine-induced changes in extrapyramidal and limbic dynorphin systems

The N-methyl-D-aspartate (NMDA)-type glutamate receptor was shown to mediate dopamine-induced dynorphin A (Dyn) changes in extrapyramidal and limbic structures. MK801, a potent noncompetitive antagonist of the NMDA receptor, blocked increases in striatal and nigral Dyn content following single and m...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 1991-08, Vol.555 (2), p.233-238
Hauptverfasser:	SINGH, N. A, MIDGLEY, L. P, BUSH, L. G, GIBB, J. W, HANSON, G. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Corpus Striatum - drug effects Corpus Striatum - metabolism Dizocilpine Maleate - pharmacology Dopamine - pharmacology Dynorphins - physiology Extrapyramidal Tracts - anatomy & histology Extrapyramidal Tracts - drug effects Extrapyramidal Tracts - physiology Fundamental and applied biological sciences. Psychology In Vitro Techniques Limbic System - anatomy & histology Limbic System - drug effects Limbic System - physiology Male Methamphetamine - pharmacology N-Methylaspartate - pharmacology Nucleus Accumbens - drug effects Nucleus Accumbens - metabolism Radioimmunoassay Rats Rats, Inbred Strains Receptors, Dopamine - drug effects Receptors, Dopamine - metabolism Receptors, Dopamine D1 Receptors, Dopamine D2 Receptors, N-Methyl-D-Aspartate - physiology Substantia Nigra - drug effects Substantia Nigra - metabolism Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!