Myotonic dystrophy : predictive value of normal results on clinical examination

Myotonic dystrophy (DM) is well known for its highly variable clinical picture, including the age at which symptoms are first detected. In order to assess the proportion of asymptomatic gene carriers at different ages, we have used linked DNA markers to study individuals at 50% genetic risk of DM, i...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 1991-10, Vol.114 (5), p.2303-2311
Hauptverfasser:	BRUNNER, H. G, SMEETS, H. J. M, ROPERS, H.-H, NILLESEN, W, VAN OOST, B. A, VAN DEN BIZENBOS, J. B. M, JOOSTEN, E. M. G, PINCKERS, A. J. L. G, HAMEL, B. C. J, THEEUWES, A. G. M, WIERINGA, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers DNA - analysis DNA Probes Heterozygote Humans Medical sciences Myotonic Dystrophy - genetics Neurology
Online-Zugang:	Volltext
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