Anti-idiotypic antibody specific for an infectious bursal disease virus-neutralizing monoclonal antibody does not interfere with the virus infection

Infectious bursal disease virus (IBDV) capsid protein, VP2, contains a hypervariable domain that is recognized by virus-neutralizing antibodies. The virus-neutralizing epitope is highly conformation-dependent and the domain is speculated to be involved in the virus-target cell interaction. In this s...

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Veröffentlicht in:	Archives of virology 2002-10, Vol.147 (10), p.2017-2023
Hauptverfasser:	YAMAGUCHI, T, IGUSA, A, SETIYONO, A, FUKUSHI, H, HIRAI, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Anti-Idiotypic - immunology Antibodies, Monoclonal - immunology Antibodies, Viral - immunology Biological and medical sciences Birnaviridae Infections - prevention & control Experimental viral diseases and models Infectious bursal disease virus - immunology Infectious diseases Medical sciences Neutralization Tests Rabbits Viral diseases Viral Structural Proteins - immunology
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