The hypercycle. Coupling of RNA and protein biosynthesis in the infection cycle of an RNA bacteriophage
It is necessary not only to describe hypercycles in vivo but also to reduce the chemical steps involved to an in vitro level where the tools of biochemistry, and in particular biochemical kinetics, can be applied for analysis. We were able to do this for a particular example, the infection cycle of...
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| Veröffentlicht in: | Biochemistry (Easton) 1991-11, Vol.30 (46), p.11005-11018 |
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| container_end_page | 11018 |
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| container_issue | 46 |
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| container_title | Biochemistry (Easton) |
| container_volume | 30 |
| creator | Eigen, Manfred Biebricher, Christof K Gebinoga, Michael Gardiner, William C |
| description | It is necessary not only to describe hypercycles in vivo but also to reduce the chemical steps involved to an in vitro level where the tools of biochemistry, and in particular biochemical kinetics, can be applied for analysis. We were able to do this for a particular example, the infection cycle of the coliphage Q beta . |
| doi_str_mv | 10.1021/bi00110a001 |
| format | Article |
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Coupling of RNA and protein biosynthesis in the infection cycle of an RNA bacteriophage</title><source>ACS Publications</source><source>MEDLINE</source><creator>Eigen, Manfred ; Biebricher, Christof K ; Gebinoga, Michael ; Gardiner, William C</creator><creatorcontrib>Eigen, Manfred ; Biebricher, Christof K ; Gebinoga, Michael ; Gardiner, William C</creatorcontrib><description>It is necessary not only to describe hypercycles in vivo but also to reduce the chemical steps involved to an in vitro level where the tools of biochemistry, and in particular biochemical kinetics, can be applied for analysis. 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Psychology</subject><subject>Microbiology</subject><subject>Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains</subject><subject>RNA Phages - growth & development</subject><subject>RNA Phages - metabolism</subject><subject>RNA, Viral - biosynthesis</subject><subject>Viral Proteins - biosynthesis</subject><subject>Virology</subject><subject>Virus Replication</subject><issn>0006-2960</issn><issn>1520-4995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEFv1DAQhS1EVbaFE2ekHBA9oLRjO3aSY1kBrVSVChau1sSZ7Lpkk9ROJPbf421WhQMSkuXxaL55en6MveZwzkHwi8oBcA4Y72dswZWANCtL9ZwtAECnotTwgp2EcB_bDPLsmB3zUgoQasHWqw0lm91A3u5sS-fJsp-G1nXrpG-Sr7eXCXZ1Mvh-JNcllevDrhs3FFxIYh9fsTRkR9d3yaPAfg27x80K7Uje9cMG1_SSHTXYBnp1qKfs-6ePq-VVevPl8_Xy8ibFrIAxlVLmkgqBtSpF_ASiFUS2hFJRnRfQ2FoCV4XNQTSgS9RWY8WhFkoWAKU8Ze9m3ej5YaIwmq0LltoWO-qnYHLBdSHj-R_INdeZyPIIvp9B6_sQPDVm8G6Lfmc4mH3-5q_8I_3mIDtVW6r_sHPgcf72MMdgsW08dtaFJ0xxJRVkEUtnzIWRfj2N0f80Ope5Mqu7byb7cSs_cH1l9ibPZh5tMPf95LsY8j8N_gbkpKZp</recordid><startdate>19911119</startdate><enddate>19911119</enddate><creator>Eigen, Manfred</creator><creator>Biebricher, Christof K</creator><creator>Gebinoga, Michael</creator><creator>Gardiner, William C</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19911119</creationdate><title>The hypercycle. 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| ispartof | Biochemistry (Easton), 1991-11, Vol.30 (46), p.11005-11018 |
| issn | 0006-2960 1520-4995 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72168368 |
| source | ACS Publications; MEDLINE |
| subjects | Biological and medical sciences Fundamental and applied biological sciences. Psychology Microbiology Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains RNA Phages - growth & development RNA Phages - metabolism RNA, Viral - biosynthesis Viral Proteins - biosynthesis Virology Virus Replication |
| title | The hypercycle. Coupling of RNA and protein biosynthesis in the infection cycle of an RNA bacteriophage |
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