Identification and characterization of a third gastrin response element (GAS-RE3) in the human histidine decarboxylase gene promoter

In human gastric cancer cells the human histidine decarboxylase gene is regulated by gastrin through two overlapping cis-acting elements known as gastrin response elements 1&2 (GAS-RE1, GAS-RE2) [J. Biol. Chem. 274 (1999) 20961]. Here, we report the identification and characterization of a third...

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Veröffentlicht in:	Biochemical and biophysical research communications 2002-10, Vol.297 (5), p.1089-1095
Hauptverfasser:	Raychowdhury, Raktima, Fleming, John V, McLaughlin, John T, Bulitta, Clemens J, Wang, Timothy C
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Binding Sites Blotting, Southern Blotting, Western Cross-Linking Reagents - pharmacology Gastrin response elements Gastrins - genetics Gastrins - metabolism Genes, Reporter Histidine decarboxylase Histidine Decarboxylase - genetics Humans Molecular Sequence Data Mutation Oligonucleotides - genetics Promoter Regions, Genetic Protein Binding Response Elements Transcription factors Transfection Ultraviolet Rays
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