Statins as anti-inflammatory agents

The beneficial effects of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) in cardiovascular disease have generally been attributed to their cholesterol-lowering property. However, an increasing number of in vitro and in vivo studies indicate that statins have direct an...

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Veröffentlicht in:	Trends in Pharmacological Sciences 2002-10, Vol.23 (10), p.482-487
1. Verfasser:	Weitz-Schmidt, Gabriele
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - pharmacology HMG-CoA reductase inhibitors Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology inflammation Interleukin-8 - pharmacology leukocyte adhesion lymphocyte function-associated antigen 1 prenylation statins
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