Human peripheral blood Valpha24+ Vbeta11+ NKT cells expand following administration of alpha-galactosylceramide-pulsed dendritic cells

We have undertaken the first clinical trial involving the administration of alpha-GalactosylCeramine (alpha-GalCer)-pulsed dendritic cells (DCs) to human subjects, to determine safety, optimal dose, optimal administration route and immunological effects. Subjects (n = 4) with metastatic malignancy r...

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Veröffentlicht in:Vox sanguinis 2002-10, Vol.83 (3), p.250-253
Hauptverfasser: Okai, M, Nieda, M, Tazbirkova, A, Horley, D, Kikuchi, A, Durrant, S, Takahashi, T, Boyd, A, Abraham, R, Yagita, H, Juji, T, Nicol, A
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