Declining value of preoperative autologous donation

BACKGROUND: Preoperative autologous blood donation (PABD) has been shown to decrease allogeneic blood transfusion requirements in major elective surgery. Changes in transfusion practice motivated an examination of blood use from 1993 to 2000 of patients participating in the Héma‐Québec PABD program....

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Veröffentlicht in:Transfusion (Philadelphia, Pa.) Pa.), 2002-07, Vol.42 (7), p.819-823
Hauptverfasser: Goldman, Mindy, Savard, Renée, Long, Anne, Gélinas, Stéphanie, Germain, Marc
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container_end_page 823
container_issue 7
container_start_page 819
container_title Transfusion (Philadelphia, Pa.)
container_volume 42
creator Goldman, Mindy
Savard, Renée
Long, Anne
Gélinas, Stéphanie
Germain, Marc
description BACKGROUND: Preoperative autologous blood donation (PABD) has been shown to decrease allogeneic blood transfusion requirements in major elective surgery. Changes in transfusion practice motivated an examination of blood use from 1993 to 2000 of patients participating in the Héma‐Québec PABD program. STUDY DESIGN AND METHODS: Blood donation and transfusion, type of surgery, and demographic characteristics were prospectively entered into a computer database for patients participating in the Héma‐Québec PABD program. RESULTS: Autologous donations represented from 0.8 to 2 percent of total blood collections and have declined by 26 percent after peaking in 1995. The mean number of units collected per patient declined, as did the number of units transfused per patient and the utilization rate. For radical prostatectomy, knee replacement surgery, hip replacement surgery, and scoliosis, utilization rates were 72, 60, 83, and 78 percent in 1993 compared with 50, 50, 58, and 58 percent in 2000, respectively. In 2000, 18 percent of patients were receiving a 1‐unit autologous transfusion. Depending on the surgical procedure, 85 to 95 percent of patients avoided allogeneic transfusion; this did not change significantly from 1993 to 2000. CONCLUSION: Patients participating in the PABD program successfully avoided allogeneic transfusion in over 85 percent of cases. However, declining utilization rates and frequent 1‐unit transfusions demonstrate the decreasing utility of PABD over time.
doi_str_mv 10.1046/j.1537-2995.2002.00132.x
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Changes in transfusion practice motivated an examination of blood use from 1993 to 2000 of patients participating in the Héma‐Québec PABD program. STUDY DESIGN AND METHODS: Blood donation and transfusion, type of surgery, and demographic characteristics were prospectively entered into a computer database for patients participating in the Héma‐Québec PABD program. RESULTS: Autologous donations represented from 0.8 to 2 percent of total blood collections and have declined by 26 percent after peaking in 1995. The mean number of units collected per patient declined, as did the number of units transfused per patient and the utilization rate. For radical prostatectomy, knee replacement surgery, hip replacement surgery, and scoliosis, utilization rates were 72, 60, 83, and 78 percent in 1993 compared with 50, 50, 58, and 58 percent in 2000, respectively. In 2000, 18 percent of patients were receiving a 1‐unit autologous transfusion. Depending on the surgical procedure, 85 to 95 percent of patients avoided allogeneic transfusion; this did not change significantly from 1993 to 2000. CONCLUSION: Patients participating in the PABD program successfully avoided allogeneic transfusion in over 85 percent of cases. However, declining utilization rates and frequent 1‐unit transfusions demonstrate the decreasing utility of PABD over time.</description><identifier>ISSN: 0041-1132</identifier><identifier>EISSN: 1537-2995</identifier><identifier>DOI: 10.1046/j.1537-2995.2002.00132.x</identifier><identifier>PMID: 12375652</identifier><identifier>CODEN: TRANAT</identifier><language>eng</language><publisher>Boston, MA, USA: Blackwell Science Inc</publisher><subject>Adolescent ; Aged ; Anesthesia. Intensive care medicine. Transfusions. 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Changes in transfusion practice motivated an examination of blood use from 1993 to 2000 of patients participating in the Héma‐Québec PABD program. STUDY DESIGN AND METHODS: Blood donation and transfusion, type of surgery, and demographic characteristics were prospectively entered into a computer database for patients participating in the Héma‐Québec PABD program. RESULTS: Autologous donations represented from 0.8 to 2 percent of total blood collections and have declined by 26 percent after peaking in 1995. The mean number of units collected per patient declined, as did the number of units transfused per patient and the utilization rate. For radical prostatectomy, knee replacement surgery, hip replacement surgery, and scoliosis, utilization rates were 72, 60, 83, and 78 percent in 1993 compared with 50, 50, 58, and 58 percent in 2000, respectively. In 2000, 18 percent of patients were receiving a 1‐unit autologous transfusion. Depending on the surgical procedure, 85 to 95 percent of patients avoided allogeneic transfusion; this did not change significantly from 1993 to 2000. CONCLUSION: Patients participating in the PABD program successfully avoided allogeneic transfusion in over 85 percent of cases. However, declining utilization rates and frequent 1‐unit transfusions demonstrate the decreasing utility of PABD over time.</description><subject>Adolescent</subject><subject>Aged</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Arthroplasty, Replacement</subject><subject>Biological and medical sciences</subject><subject>Blood Transfusion - statistics &amp; numerical data</subject><subject>Blood Transfusion - trends</subject><subject>Blood Transfusion, Autologous - statistics &amp; numerical data</subject><subject>Blood Transfusion, Autologous - trends</subject><subject>Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis</subject><subject>Databases, Factual</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Practice Guidelines as Topic</subject><subject>Preoperative Care - statistics &amp; numerical data</subject><subject>Preoperative Care - trends</subject><subject>Prostatectomy</subject><subject>Scoliosis - surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgical Procedures, Operative - trends</subject><subject>Transfusions. Complications. Transfusion reactions. 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Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Arthroplasty, Replacement</topic><topic>Biological and medical sciences</topic><topic>Blood Transfusion - statistics &amp; numerical data</topic><topic>Blood Transfusion - trends</topic><topic>Blood Transfusion, Autologous - statistics &amp; numerical data</topic><topic>Blood Transfusion, Autologous - trends</topic><topic>Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis</topic><topic>Databases, Factual</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Practice Guidelines as Topic</topic><topic>Preoperative Care - statistics &amp; numerical data</topic><topic>Preoperative Care - trends</topic><topic>Prostatectomy</topic><topic>Scoliosis - surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgical Procedures, Operative - trends</topic><topic>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Goldman, Mindy</creatorcontrib><creatorcontrib>Savard, Renée</creatorcontrib><creatorcontrib>Long, Anne</creatorcontrib><creatorcontrib>Gélinas, Stéphanie</creatorcontrib><creatorcontrib>Germain, Marc</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Transfusion (Philadelphia, Pa.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goldman, Mindy</au><au>Savard, Renée</au><au>Long, Anne</au><au>Gélinas, Stéphanie</au><au>Germain, Marc</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Declining value of preoperative autologous donation</atitle><jtitle>Transfusion (Philadelphia, Pa.)</jtitle><addtitle>Transfusion</addtitle><date>2002-07</date><risdate>2002</risdate><volume>42</volume><issue>7</issue><spage>819</spage><epage>823</epage><pages>819-823</pages><issn>0041-1132</issn><eissn>1537-2995</eissn><coden>TRANAT</coden><abstract>BACKGROUND: Preoperative autologous blood donation (PABD) has been shown to decrease allogeneic blood transfusion requirements in major elective surgery. 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subjects Adolescent
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Arthroplasty, Replacement
Biological and medical sciences
Blood Transfusion - statistics & numerical data
Blood Transfusion - trends
Blood Transfusion, Autologous - statistics & numerical data
Blood Transfusion, Autologous - trends
Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis
Databases, Factual
Female
Humans
Male
Medical sciences
Middle Aged
Miscellaneous
Practice Guidelines as Topic
Preoperative Care - statistics & numerical data
Preoperative Care - trends
Prostatectomy
Scoliosis - surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgical Procedures, Operative - trends
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
title Declining value of preoperative autologous donation
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