Declining value of preoperative autologous donation
BACKGROUND: Preoperative autologous blood donation (PABD) has been shown to decrease allogeneic blood transfusion requirements in major elective surgery. Changes in transfusion practice motivated an examination of blood use from 1993 to 2000 of patients participating in the Héma‐Québec PABD program....
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Veröffentlicht in: | Transfusion (Philadelphia, Pa.) Pa.), 2002-07, Vol.42 (7), p.819-823 |
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creator | Goldman, Mindy Savard, Renée Long, Anne Gélinas, Stéphanie Germain, Marc |
description | BACKGROUND: Preoperative autologous blood donation (PABD) has been shown to decrease allogeneic blood transfusion requirements in major elective surgery. Changes in transfusion practice motivated an examination of blood use from 1993 to 2000 of patients participating in the Héma‐Québec PABD program.
STUDY DESIGN AND METHODS: Blood donation and transfusion, type of surgery, and demographic characteristics were prospectively entered into a computer database for patients participating in the Héma‐Québec PABD program.
RESULTS: Autologous donations represented from 0.8 to 2 percent of total blood collections and have declined by 26 percent after peaking in 1995. The mean number of units collected per patient declined, as did the number of units transfused per patient and the utilization rate. For radical prostatectomy, knee replacement surgery, hip replacement surgery, and scoliosis, utilization rates were 72, 60, 83, and 78 percent in 1993 compared with 50, 50, 58, and 58 percent in 2000, respectively. In 2000, 18 percent of patients were receiving a 1‐unit autologous transfusion. Depending on the surgical procedure, 85 to 95 percent of patients avoided allogeneic transfusion; this did not change significantly from 1993 to 2000.
CONCLUSION: Patients participating in the PABD program successfully avoided allogeneic transfusion in over 85 percent of cases. However, declining utilization rates and frequent 1‐unit transfusions demonstrate the decreasing utility of PABD over time. |
doi_str_mv | 10.1046/j.1537-2995.2002.00132.x |
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STUDY DESIGN AND METHODS: Blood donation and transfusion, type of surgery, and demographic characteristics were prospectively entered into a computer database for patients participating in the Héma‐Québec PABD program.
RESULTS: Autologous donations represented from 0.8 to 2 percent of total blood collections and have declined by 26 percent after peaking in 1995. The mean number of units collected per patient declined, as did the number of units transfused per patient and the utilization rate. For radical prostatectomy, knee replacement surgery, hip replacement surgery, and scoliosis, utilization rates were 72, 60, 83, and 78 percent in 1993 compared with 50, 50, 58, and 58 percent in 2000, respectively. In 2000, 18 percent of patients were receiving a 1‐unit autologous transfusion. Depending on the surgical procedure, 85 to 95 percent of patients avoided allogeneic transfusion; this did not change significantly from 1993 to 2000.
CONCLUSION: Patients participating in the PABD program successfully avoided allogeneic transfusion in over 85 percent of cases. However, declining utilization rates and frequent 1‐unit transfusions demonstrate the decreasing utility of PABD over time.</description><identifier>ISSN: 0041-1132</identifier><identifier>EISSN: 1537-2995</identifier><identifier>DOI: 10.1046/j.1537-2995.2002.00132.x</identifier><identifier>PMID: 12375652</identifier><identifier>CODEN: TRANAT</identifier><language>eng</language><publisher>Boston, MA, USA: Blackwell Science Inc</publisher><subject>Adolescent ; Aged ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Arthroplasty, Replacement ; Biological and medical sciences ; Blood Transfusion - statistics & numerical data ; Blood Transfusion - trends ; Blood Transfusion, Autologous - statistics & numerical data ; Blood Transfusion, Autologous - trends ; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis ; Databases, Factual ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Miscellaneous ; Practice Guidelines as Topic ; Preoperative Care - statistics & numerical data ; Preoperative Care - trends ; Prostatectomy ; Scoliosis - surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgical Procedures, Operative - trends ; Transfusions. Complications. Transfusion reactions. Cell and gene therapy</subject><ispartof>Transfusion (Philadelphia, Pa.), 2002-07, Vol.42 (7), p.819-823</ispartof><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5272-3eaff9f30c8a0f567a4b5514bf2cd68dbbc5f2de1d5003a079e8dbc932e4e9ab3</citedby><cites>FETCH-LOGICAL-c5272-3eaff9f30c8a0f567a4b5514bf2cd68dbbc5f2de1d5003a079e8dbc932e4e9ab3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1046%2Fj.1537-2995.2002.00132.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1046%2Fj.1537-2995.2002.00132.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13823255$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12375652$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Goldman, Mindy</creatorcontrib><creatorcontrib>Savard, Renée</creatorcontrib><creatorcontrib>Long, Anne</creatorcontrib><creatorcontrib>Gélinas, Stéphanie</creatorcontrib><creatorcontrib>Germain, Marc</creatorcontrib><title>Declining value of preoperative autologous donation</title><title>Transfusion (Philadelphia, Pa.)</title><addtitle>Transfusion</addtitle><description>BACKGROUND: Preoperative autologous blood donation (PABD) has been shown to decrease allogeneic blood transfusion requirements in major elective surgery. Changes in transfusion practice motivated an examination of blood use from 1993 to 2000 of patients participating in the Héma‐Québec PABD program.
STUDY DESIGN AND METHODS: Blood donation and transfusion, type of surgery, and demographic characteristics were prospectively entered into a computer database for patients participating in the Héma‐Québec PABD program.
RESULTS: Autologous donations represented from 0.8 to 2 percent of total blood collections and have declined by 26 percent after peaking in 1995. The mean number of units collected per patient declined, as did the number of units transfused per patient and the utilization rate. For radical prostatectomy, knee replacement surgery, hip replacement surgery, and scoliosis, utilization rates were 72, 60, 83, and 78 percent in 1993 compared with 50, 50, 58, and 58 percent in 2000, respectively. In 2000, 18 percent of patients were receiving a 1‐unit autologous transfusion. Depending on the surgical procedure, 85 to 95 percent of patients avoided allogeneic transfusion; this did not change significantly from 1993 to 2000.
CONCLUSION: Patients participating in the PABD program successfully avoided allogeneic transfusion in over 85 percent of cases. However, declining utilization rates and frequent 1‐unit transfusions demonstrate the decreasing utility of PABD over time.</description><subject>Adolescent</subject><subject>Aged</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Arthroplasty, Replacement</subject><subject>Biological and medical sciences</subject><subject>Blood Transfusion - statistics & numerical data</subject><subject>Blood Transfusion - trends</subject><subject>Blood Transfusion, Autologous - statistics & numerical data</subject><subject>Blood Transfusion, Autologous - trends</subject><subject>Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis</subject><subject>Databases, Factual</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Practice Guidelines as Topic</subject><subject>Preoperative Care - statistics & numerical data</subject><subject>Preoperative Care - trends</subject><subject>Prostatectomy</subject><subject>Scoliosis - surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgical Procedures, Operative - trends</subject><subject>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</subject><issn>0041-1132</issn><issn>1537-2995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMtKAzEUhoMotl5eQWajuxlzmcwF3Ei1VfBGqQhuQiZzUqZOJzXpaN0JvqlPYmpL3bpKOOf7k58PoYDgiOA4OZ1EhLM0pHnOI4oxjTAmjEaLLdTdLLZRF-OYhMRvOmjPuQn2ZI7JLuoQylKecNpF_AJUXTVVMw7eZN1CYHQws2BmYOW8eoNAtnNTm7Fp3ffnV2kaPzXNAdrRsnZwuD730WP_ctS7Cm_uB9e985tQcZrSkIHUOtcMq0xizZNUxgXnJC40VWWSlUWhuKYlkJJjzCROc_BDlTMKMeSyYPvoZPXuzJrXFtxcTCunoK5lA76RSClJaMZSD2YrUFnjnAUtZraaSvshCBZLZWIilmbE0oxYKhO_ysTCR4_Wf7TFFMq_4NqRB47XgHRK1trKRlXuj2MZZZRzz52tuPeqho9_FxCjYd9ffDxcxSs3h8UmLu2LSFJfRTzdDcTt1TPjD8O-GLAfnLaXrg</recordid><startdate>200207</startdate><enddate>200207</enddate><creator>Goldman, Mindy</creator><creator>Savard, Renée</creator><creator>Long, Anne</creator><creator>Gélinas, Stéphanie</creator><creator>Germain, Marc</creator><general>Blackwell Science Inc</general><general>Blackwell Publishing</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200207</creationdate><title>Declining value of preoperative autologous donation</title><author>Goldman, Mindy ; Savard, Renée ; Long, Anne ; Gélinas, Stéphanie ; Germain, Marc</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5272-3eaff9f30c8a0f567a4b5514bf2cd68dbbc5f2de1d5003a079e8dbc932e4e9ab3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adolescent</topic><topic>Aged</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Arthroplasty, Replacement</topic><topic>Biological and medical sciences</topic><topic>Blood Transfusion - statistics & numerical data</topic><topic>Blood Transfusion - trends</topic><topic>Blood Transfusion, Autologous - statistics & numerical data</topic><topic>Blood Transfusion, Autologous - trends</topic><topic>Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis</topic><topic>Databases, Factual</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Practice Guidelines as Topic</topic><topic>Preoperative Care - statistics & numerical data</topic><topic>Preoperative Care - trends</topic><topic>Prostatectomy</topic><topic>Scoliosis - surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgical Procedures, Operative - trends</topic><topic>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Goldman, Mindy</creatorcontrib><creatorcontrib>Savard, Renée</creatorcontrib><creatorcontrib>Long, Anne</creatorcontrib><creatorcontrib>Gélinas, Stéphanie</creatorcontrib><creatorcontrib>Germain, Marc</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Transfusion (Philadelphia, Pa.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goldman, Mindy</au><au>Savard, Renée</au><au>Long, Anne</au><au>Gélinas, Stéphanie</au><au>Germain, Marc</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Declining value of preoperative autologous donation</atitle><jtitle>Transfusion (Philadelphia, Pa.)</jtitle><addtitle>Transfusion</addtitle><date>2002-07</date><risdate>2002</risdate><volume>42</volume><issue>7</issue><spage>819</spage><epage>823</epage><pages>819-823</pages><issn>0041-1132</issn><eissn>1537-2995</eissn><coden>TRANAT</coden><abstract>BACKGROUND: Preoperative autologous blood donation (PABD) has been shown to decrease allogeneic blood transfusion requirements in major elective surgery. Changes in transfusion practice motivated an examination of blood use from 1993 to 2000 of patients participating in the Héma‐Québec PABD program.
STUDY DESIGN AND METHODS: Blood donation and transfusion, type of surgery, and demographic characteristics were prospectively entered into a computer database for patients participating in the Héma‐Québec PABD program.
RESULTS: Autologous donations represented from 0.8 to 2 percent of total blood collections and have declined by 26 percent after peaking in 1995. The mean number of units collected per patient declined, as did the number of units transfused per patient and the utilization rate. For radical prostatectomy, knee replacement surgery, hip replacement surgery, and scoliosis, utilization rates were 72, 60, 83, and 78 percent in 1993 compared with 50, 50, 58, and 58 percent in 2000, respectively. In 2000, 18 percent of patients were receiving a 1‐unit autologous transfusion. Depending on the surgical procedure, 85 to 95 percent of patients avoided allogeneic transfusion; this did not change significantly from 1993 to 2000.
CONCLUSION: Patients participating in the PABD program successfully avoided allogeneic transfusion in over 85 percent of cases. However, declining utilization rates and frequent 1‐unit transfusions demonstrate the decreasing utility of PABD over time.</abstract><cop>Boston, MA, USA</cop><pub>Blackwell Science Inc</pub><pmid>12375652</pmid><doi>10.1046/j.1537-2995.2002.00132.x</doi><tpages>5</tpages></addata></record> |
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subjects | Adolescent Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Arthroplasty, Replacement Biological and medical sciences Blood Transfusion - statistics & numerical data Blood Transfusion - trends Blood Transfusion, Autologous - statistics & numerical data Blood Transfusion, Autologous - trends Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Databases, Factual Female Humans Male Medical sciences Middle Aged Miscellaneous Practice Guidelines as Topic Preoperative Care - statistics & numerical data Preoperative Care - trends Prostatectomy Scoliosis - surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgical Procedures, Operative - trends Transfusions. Complications. Transfusion reactions. Cell and gene therapy |
title | Declining value of preoperative autologous donation |
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