Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation

The NF-kappaB family of transcription factors is critical in controlling the expression of a wide range of immune response genes. However, whether individual family members perform specific roles in regulating immunity and inflammation remains unclear. Here we investigated the requirement for NF-kap...

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Veröffentlicht in:	The Journal of immunology (1950) 2002-10, Vol.169 (8), p.4481-4487
Hauptverfasser:	Artis, David, Shapira, Sagi, Mason, Nicola, Speirs, Kendra M, Goldschmidt, Michael, Caamaño, Jorge, Liou, Hsiou-Chi, Hunter, Christopher A, Scott, Phillip
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Chronic Disease Colitis - genetics Colitis - immunology Colitis - pathology Cytokines - biosynthesis Epitopes, T-Lymphocyte - immunology Immunity, Innate - genetics Interleukin-12 - antagonists & inhibitors Interleukin-12 - physiology Interleukin-13 - biosynthesis Intestinal Diseases, Parasitic - genetics Intestinal Diseases, Parasitic - immunology Intestinal Diseases, Parasitic - parasitology Intestinal Diseases, Parasitic - pathology Mice Mice, Inbred C57BL Mice, Knockout Multigene Family - immunology NF-kappa B - deficiency NF-kappa B - genetics NF-kappa B - physiology NF-kappa B p50 Subunit NF-kappa B p52 Subunit Proto-Oncogene Proteins c-rel - deficiency Proto-Oncogene Proteins c-rel - genetics Proto-Oncogene Proteins c-rel - physiology Trichuriasis - genetics Trichuriasis - immunology Trichuriasis - parasitology Trichuriasis - pathology Trichuris - immunology
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