Fiber-type specific and position-dependent expression of a transgene in limb muscles

We have previously shown that the proximal sequences of the human aldolase A fast-muscle-specific promoter (pM) are sufficient to target the expression of a linked CAT reporter gene to all fast, glycolytic trunk and limb muscles of transgenic mice (pM310CAT lines) in a manner mimicking the activity...

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Veröffentlicht in:	Differentiation (London) 2002-10, Vol.70 (8), p.457-467
Hauptverfasser:	Spitz, François, Benbacer, Laïla, Salminen, Marjo, Kahn, Axel, Maire, Pascal, Daegelen, Dominique, Sabourin, Jean-Christophe, Chen, Fengmei, Cywiner, Charlotte, Chatelet, François
Format:	Artikel
Sprache:	eng
Schlagworte:	aldolase A Amino Acid Motifs - genetics Animals Biological and medical sciences Cell differentiation, maturation, development, hematopoiesis Cell physiology Chloramphenicol O-Acetyltransferase - genetics Fructose-Bisphosphate Aldolase - genetics Fundamental and applied biological sciences. Psychology Gene Transfer Techniques Genes, Reporter Hindlimb - metabolism Mice Mice, Transgenic Molecular and cellular biology muscle diversity Muscles - metabolism positional identity Promoter Regions, Genetic Transgenes
Online-Zugang:	Volltext
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