Saccharide Orientation at the Cell Surface Affects Glycolipid Receptor Function

Three allelic variants of P-pilus-associated G-adhesins (lectins) with different cell-binding properties were recently described. Here we have analyzed Escherichia coli HB101 strains expressing the recombinant G-adhesin variants for their ability to agglutinate erythrocytes from various species as t...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1991-10, Vol.88 (20), p.9340-9344
Hauptverfasser:	Stromberg, Nicklas, Nyholm, Per-Georg, Pascher, Irmin, Normark, Staffan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins, Escherichia coli Agglutination Animals Bacteria Bacterial Adhesion Bacterial Outer Membrane Proteins - genetics Bacterial Outer Membrane Proteins - metabolism Bacteriology Biological and medical sciences Carbohydrate Conformation Carbohydrate Sequence Cell lines Epitopes Erythrocyte membrane Erythrocytes Erythrocytes - physiology Escherichia coli - genetics Escherichia coli - physiology Fundamental and applied biological sciences. Psychology Genetic Variation Glycolipids Glycolipids - blood glycosphingolipids Hemagglutination Humans Microbiology Models, Molecular Molecular Sequence Data P branes Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Receptors Receptors, Mitogen - physiology saccharides
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