Failure of Pentoxifylline or Cilostazol to Improve Blood and Plasma Viscosity, Fibrinogen, and Erythrocyte Deformability in Claudication

Peripheral artery disease is associated with altered blood rheologic properties, including increased viscosity and decreased red blood cell (RBC) deformability. Pentoxifylline and cilostazol are available therapies for intermittent claudication. Improvement of blood viscosity and erythrocyte deforma...

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Veröffentlicht in:	Angiology 2002-09, Vol.53 (5), p.509-520
Hauptverfasser:	Dawson, David L., Qintian Zheng, Worthy, Sue A., Charles, Brandie, Bradley, Donald V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis of Variance Biological and medical sciences Blood Viscosity - drug effects Cardiovascular system Data Interpretation, Statistical Double-Blind Method Drug therapy Erythrocyte Deformability - drug effects Evaluation Female Fibrinogen - drug effects Humans Intermittent claudication Intermittent Claudication - blood Intermittent Claudication - drug therapy Male Medical sciences Middle Aged Models, Biological Pentoxifylline Pentoxifylline - pharmacology Pentoxifylline - therapeutic use Peripheral vascular diseases Pharmacology. Drug treatments Placebos Platelet Aggregation Inhibitors - pharmacology Platelet Aggregation Inhibitors - therapeutic use Prospective Studies Tetrazoles - pharmacology Tetrazoles - therapeutic use Time Factors Vasodilator Agents - pharmacology Vasodilator Agents - therapeutic use Vasodilator agents. Cerebral vasodilators Walking
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