Comorbidity of depression with other medical diseases in the elderly
A major factor in the context of evaluating depression in the elderly is the role of medical problems. With aging there is a rapid increase in the prevalence of a number of medical disorders, including cancer, heart disease, Parkinson’s disease, Alzheimer’s disease, stroke, and arthritis. In this ar...
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| Veröffentlicht in: | Biological Psychiatry 2002-09, Vol.52 (6), p.559-588 |
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| container_title | Biological Psychiatry |
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| creator | Krishnan, K.Ranga R Delong, Mahlon Kraemer, Helena Carney, Robert Spiegel, David Gordon, Christopher McDonald, William Dew, Mary Amanda Alexopoulos, George Buckwalter, Kathleen Cohen, Perry D Evans, Dwight Kaufmann, Peter G Olin, Jason Otey, Emeline Wainscott, Cynthia |
| description | A major factor in the context of evaluating depression in the elderly is the role of medical problems. With aging there is a rapid increase in the prevalence of a number of medical disorders, including cancer, heart disease, Parkinson’s disease, Alzheimer’s disease, stroke, and arthritis. In this article, we hope to bring clarity to the definition of comorbidity and then discuss a number of medical disorders as they relate to depression. We evaluate medical comorbidity as a risk factor for depression as well as the converse, that is, depression as a risk factor for medical illness. Most of the disorders that we focus on occur in the elderly, with the exception of HIV infection. This review focuses exclusively on unipolar disorder. The review summarizes the current state of the art and also makes recommendations for future directions. |
| doi_str_mv | 10.1016/S0006-3223(02)01472-5 |
| format | Article |
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With aging there is a rapid increase in the prevalence of a number of medical disorders, including cancer, heart disease, Parkinson’s disease, Alzheimer’s disease, stroke, and arthritis. In this article, we hope to bring clarity to the definition of comorbidity and then discuss a number of medical disorders as they relate to depression. We evaluate medical comorbidity as a risk factor for depression as well as the converse, that is, depression as a risk factor for medical illness. Most of the disorders that we focus on occur in the elderly, with the exception of HIV infection. This review focuses exclusively on unipolar disorder. The review summarizes the current state of the art and also makes recommendations for future directions.</description><identifier>ISSN: 0006-3223</identifier><identifier>EISSN: 1873-2402</identifier><identifier>DOI: 10.1016/S0006-3223(02)01472-5</identifier><identifier>PMID: 12361669</identifier><identifier>CODEN: BIPCBF</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Acquired Immunodeficiency Syndrome - epidemiology ; Adult and adolescent clinical studies ; Age ; Aged ; Biological and medical sciences ; cancer ; cardiac ; Cardiovascular Diseases - epidemiology ; Comorbidity ; Depression ; Depressive Disorder - diagnosis ; Depressive Disorder - epidemiology ; Depressive Disorder - therapy ; Geriatrics ; HIV ; Humans ; medical ; Medical sciences ; Mood disorders ; Musculoskeletal Diseases - epidemiology ; National Institute of Mental Health (U.S.) ; Neoplasms - epidemiology ; Nervous System Diseases - epidemiology ; Psychology. 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With aging there is a rapid increase in the prevalence of a number of medical disorders, including cancer, heart disease, Parkinson’s disease, Alzheimer’s disease, stroke, and arthritis. In this article, we hope to bring clarity to the definition of comorbidity and then discuss a number of medical disorders as they relate to depression. We evaluate medical comorbidity as a risk factor for depression as well as the converse, that is, depression as a risk factor for medical illness. Most of the disorders that we focus on occur in the elderly, with the exception of HIV infection. This review focuses exclusively on unipolar disorder. The review summarizes the current state of the art and also makes recommendations for future directions.</description><subject>Acquired Immunodeficiency Syndrome - epidemiology</subject><subject>Adult and adolescent clinical studies</subject><subject>Age</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>cancer</subject><subject>cardiac</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Comorbidity</subject><subject>Depression</subject><subject>Depressive Disorder - diagnosis</subject><subject>Depressive Disorder - epidemiology</subject><subject>Depressive Disorder - therapy</subject><subject>Geriatrics</subject><subject>HIV</subject><subject>Humans</subject><subject>medical</subject><subject>Medical sciences</subject><subject>Mood disorders</subject><subject>Musculoskeletal Diseases - epidemiology</subject><subject>National Institute of Mental Health (U.S.)</subject><subject>Neoplasms - epidemiology</subject><subject>Nervous System Diseases - epidemiology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Research - trends</subject><subject>Risk Factors</subject><subject>Terminology as Topic</subject><subject>Treatment Outcome</subject><subject>United States</subject><issn>0006-3223</issn><issn>1873-2402</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEQgIMoWh8_QclF0cNqMsm-TiL1CYIH9RyyySyNbDc12Sr996a22KOnYZhvXh8hx5xdcsaLq1fGWJEJAHHO4IJxWUKWb5ERr0qRgWSwTUZ_yB7Zj_EjpSUA3yV7HETBi6Iekduxn_rQOOuGBfUttTgLGKPzPf12w4T6YYKBTtE6oztqXUQdMVLX01Sg2FkM3eKQ7LS6i3i0jgfk_f7ubfyYPb88PI1vnjMjaj5kFdSlwMq2GrlkshFoZV1Aha3RNQdrywZ0IwzWVQuCVy3n1jZVLqEUuZFaHJCz1dxZ8J9zjIOaumiw63SPfh5VCTxnUsoE5ivQBB9jwFbNgpvqsFCcqaU-9atPLd0oBupXn8pT38l6wbxJP2-61r4ScLoGdExC2qB74-KGE3UuRF4m7nrFYdLx5TCoaBz2JnkMaAZlvfvnlB-omovX</recordid><startdate>20020915</startdate><enddate>20020915</enddate><creator>Krishnan, K.Ranga R</creator><creator>Delong, Mahlon</creator><creator>Kraemer, Helena</creator><creator>Carney, Robert</creator><creator>Spiegel, David</creator><creator>Gordon, Christopher</creator><creator>McDonald, William</creator><creator>Dew, Mary Amanda</creator><creator>Alexopoulos, George</creator><creator>Buckwalter, Kathleen</creator><creator>Cohen, Perry D</creator><creator>Evans, Dwight</creator><creator>Kaufmann, Peter G</creator><creator>Olin, Jason</creator><creator>Otey, Emeline</creator><creator>Wainscott, Cynthia</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020915</creationdate><title>Comorbidity of depression with other medical diseases in the elderly</title><author>Krishnan, K.Ranga R ; Delong, Mahlon ; Kraemer, Helena ; Carney, Robert ; Spiegel, David ; Gordon, Christopher ; McDonald, William ; Dew, Mary Amanda ; Alexopoulos, George ; Buckwalter, Kathleen ; Cohen, Perry D ; Evans, Dwight ; Kaufmann, Peter G ; Olin, Jason ; Otey, Emeline ; Wainscott, Cynthia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-82973e8dfae1404b3ed49628efca912dd7b2ab3ce98f2318f11ddb8542735c4a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Acquired Immunodeficiency Syndrome - epidemiology</topic><topic>Adult and adolescent clinical studies</topic><topic>Age</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>cancer</topic><topic>cardiac</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Comorbidity</topic><topic>Depression</topic><topic>Depressive Disorder - diagnosis</topic><topic>Depressive Disorder - epidemiology</topic><topic>Depressive Disorder - therapy</topic><topic>Geriatrics</topic><topic>HIV</topic><topic>Humans</topic><topic>medical</topic><topic>Medical sciences</topic><topic>Mood disorders</topic><topic>Musculoskeletal Diseases - epidemiology</topic><topic>National Institute of Mental Health (U.S.)</topic><topic>Neoplasms - epidemiology</topic><topic>Nervous System Diseases - epidemiology</topic><topic>Psychology. 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| subjects | Acquired Immunodeficiency Syndrome - epidemiology Adult and adolescent clinical studies Age Aged Biological and medical sciences cancer cardiac Cardiovascular Diseases - epidemiology Comorbidity Depression Depressive Disorder - diagnosis Depressive Disorder - epidemiology Depressive Disorder - therapy Geriatrics HIV Humans medical Medical sciences Mood disorders Musculoskeletal Diseases - epidemiology National Institute of Mental Health (U.S.) Neoplasms - epidemiology Nervous System Diseases - epidemiology Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Research - trends Risk Factors Terminology as Topic Treatment Outcome United States |
| title | Comorbidity of depression with other medical diseases in the elderly |
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