Clinical observations on lower respiratory tract infections with special reference to serum IgE levels

To examine if the occurrence of wheezing among children with lower respiratory tract infections is associated with atopic predisposition, serum levels of IgE were determined for groups of children with or without wheezing, during infection with Mycoplasma pneumoniae or respiratory syncytial virus (R...

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Veröffentlicht in:Pediatric pulmonology 1991, Vol.11 (1), p.44-48
Hauptverfasser: Nagayama, Yoko, Sakurai, Nobukiyo
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container_title Pediatric pulmonology
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creator Nagayama, Yoko
Sakurai, Nobukiyo
description To examine if the occurrence of wheezing among children with lower respiratory tract infections is associated with atopic predisposition, serum levels of IgE were determined for groups of children with or without wheezing, during infection with Mycoplasma pneumoniae or respiratory syncytial virus (RSV). In M. pneumoniae infection, more than 60% of wheezy children over 2 years of age showed a high IgE level (200 IU/mL or more), while IgE levels were less than 200 IU/mL in 73% of non‐wheezy children. In RSV infection, the incidence of high IgE levels among wheezy children was nearly double that of non‐wheezy children, although the difference was not significant. These results suggest that in children an allergic disposition is involved in the occurrence of wheezing during the course of lower respiratory tract infections.Pediatr Pulmonol. 1991; 11:44‐48
doi_str_mv 10.1002/ppul.1950110108
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source Wiley-Blackwell Journals; MEDLINE
subjects affects of age and disease stage
Age Factors
Bacterial diseases
Bacterial diseases of the respiratory system
Biological and medical sciences
Child, Preschool
Human bacterial diseases
Humans
Immunoglobulin E - blood
Infant
Infectious diseases
Medical sciences
Mycoplasma pneumoniae
Pneumonia, Mycoplasma - complications
Pneumonia, Mycoplasma - immunology
Pneumonia, Viral - complications
Pneumonia, Viral - immunology
Pneumonia, Viral - microbiology
Respiratory Sounds - etiology
Respiratory Sounds - immunology
Respiratory Syncytial Viruses - isolation & purification
Respirovirus Infections - complications
Respirovirus Infections - immunology
RSV infections
wheezy vs. non-wheezy patients
title Clinical observations on lower respiratory tract infections with special reference to serum IgE levels
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