Characteristics and outcome of patients with Philadelphia chromosome negative, bcr/abl negative chronic myelogenous leukemia

BACKGROUND Up to 5% of patients with chronic myelogenous leukemia (CML) do not have the Philadelphia (Ph) translocation t(9;22)(q34;q11) or a bcr/abl molecular rearrangement. Although the diagnostic criteria of this entity are still under debate, there is general agreement that patients with Ph nega...

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Veröffentlicht in:	Cancer 2002-10, Vol.95 (8), p.1673-1684
Hauptverfasser:	Onida, Francesco, Ball, Greg, Kantarjian, Hagop M., Smith, Terry L., Glassman, Armand, Albitar, Maher, Scappini, Barbara, Rios, Mary Beth, Keating, Michael J., Beran, Miloslav
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over bcr/abl Biological and medical sciences Chromosome Aberrations Female gene rearrangement Genes, abl - genetics Hematologic and hematopoietic diseases hematologic variables Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - genetics Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged myeloproliferative disorder Prognosis Retrospective Studies risk categories Survival Analysis
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