Benign and malignant neoplasms in a family with Peutz-Jeghers syndrome: study of three generations

Three members of a family with Peutz-Jeghers syndrome had intussusception due to intestinal hamartomas. In addition, the grandfather had carcinoma of the jejunum, and the granddaughter had benign ovarian sex cord/stromal tumor causing sexual precocity. Benign and malignant tumors, not often associat...

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Veröffentlicht in:	Southern medical journal (Birmingham, Ala.) Ala.), 1991-10, Vol.84 (10), p.1205-1209
1. Verfasser:	Laughlin, E H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - pathology Adult Child Female Gastrointestinal Neoplasms - genetics Gastrointestinal Neoplasms - pathology Humans Jejunal Neoplasms - pathology Male Neoplasms, Multiple Primary - genetics Ovarian Neoplasms - pathology Pedigree Peutz-Jeghers Syndrome - genetics Peutz-Jeghers Syndrome - pathology
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description	Three members of a family with Peutz-Jeghers syndrome had intussusception due to intestinal hamartomas. In addition, the grandfather had carcinoma of the jejunum, and the granddaughter had benign ovarian sex cord/stromal tumor causing sexual precocity. Benign and malignant tumors, not often associated with Peutz-Jeghers syndrome, pose a further threat in addition to the gastrointestinal bleeding and obstruction that often complicate this inherited syndrome.
doi_str_mv	10.1097/00007611-199110000-00011
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In addition, the grandfather had carcinoma of the jejunum, and the granddaughter had benign ovarian sex cord/stromal tumor causing sexual precocity. Benign and malignant tumors, not often associated with Peutz-Jeghers syndrome, pose a further threat in addition to the gastrointestinal bleeding and obstruction that often complicate this inherited syndrome.</description><subject>Adenocarcinoma - pathology</subject><subject>Adult</subject><subject>Child</subject><subject>Female</subject><subject>Gastrointestinal Neoplasms - genetics</subject><subject>Gastrointestinal Neoplasms - pathology</subject><subject>Humans</subject><subject>Jejunal Neoplasms - pathology</subject><subject>Male</subject><subject>Neoplasms, Multiple Primary - genetics</subject><subject>Ovarian Neoplasms - pathology</subject><subject>Pedigree</subject><subject>Peutz-Jeghers Syndrome - genetics</subject><subject>Peutz-Jeghers Syndrome - pathology</subject><issn>0038-4348</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1PwzAMhnMAjTH4CUg5cSskadok3GDiU5PgAOcobZ2tqE1HkgqNX0_GBkSyYsuvbb0PQpiSC0qUuCTpiZLSjCpF6bbKUlB6gKaE5DLjOZdH6DiE962wkOUETahihWBkiqobcO3SYeMa3JsupcZF7GBYdyb0Abepha3p226DP9u4wi8wxq_sCZYr8AGHjWv80MMVDnFsNniwOK48AF6CA29iO7hwgg6t6QKc7v8Zeru7fZ0_ZIvn-8f59SKrWcFjZhmtLbEFLwk0pCqlYHlpreVMVKzKFa1rJS2IkitDKZeSJ_clE7ZmXCaL-Qyd7_au_fAxQoi6b0MNXWeSnTFowShXpBBJKHfC2g8heLB67dve-I2mRG-R6l-k-g-p_kGaRs_2N8aqh-Z_cMcz_wZHNnNp</recordid><startdate>199110</startdate><enddate>199110</enddate><creator>Laughlin, E H</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199110</creationdate><title>Benign and malignant neoplasms in a family with Peutz-Jeghers syndrome: study of three generations</title><author>Laughlin, E H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c254t-f21cf0f5460ed0b687236fff427b2b391cc98fe7649a114884109627fc2483483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Adenocarcinoma - pathology</topic><topic>Adult</topic><topic>Child</topic><topic>Female</topic><topic>Gastrointestinal Neoplasms - genetics</topic><topic>Gastrointestinal Neoplasms - pathology</topic><topic>Humans</topic><topic>Jejunal Neoplasms - pathology</topic><topic>Male</topic><topic>Neoplasms, Multiple Primary - genetics</topic><topic>Ovarian Neoplasms - pathology</topic><topic>Pedigree</topic><topic>Peutz-Jeghers Syndrome - genetics</topic><topic>Peutz-Jeghers Syndrome - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Laughlin, E H</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Southern medical journal (Birmingham, Ala.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Laughlin, E H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Benign and malignant neoplasms in a family with Peutz-Jeghers syndrome: study of three generations</atitle><jtitle>Southern medical journal (Birmingham, Ala.)</jtitle><addtitle>South Med J</addtitle><date>1991-10</date><risdate>1991</risdate><volume>84</volume><issue>10</issue><spage>1205</spage><epage>1209</epage><pages>1205-1209</pages><issn>0038-4348</issn><abstract>Three members of a family with Peutz-Jeghers syndrome had intussusception due to intestinal hamartomas. 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source	MEDLINE; Journals@Ovid Complete
subjects	Adenocarcinoma - pathology Adult Child Female Gastrointestinal Neoplasms - genetics Gastrointestinal Neoplasms - pathology Humans Jejunal Neoplasms - pathology Male Neoplasms, Multiple Primary - genetics Ovarian Neoplasms - pathology Pedigree Peutz-Jeghers Syndrome - genetics Peutz-Jeghers Syndrome - pathology
title	Benign and malignant neoplasms in a family with Peutz-Jeghers syndrome: study of three generations
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