Nerve sheath myxoma of the tongue in a child
Nerve sheath myxoma (NSM) is a benign peripheral nervous system tumour that rarely occurs in the oral cavity. Among 17 cases of oral NSM described in the literature (average patient age 33 years), only two, including the present case, have been reported in children. The present case occurring in an...
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Veröffentlicht in: | International journal of oral and maxillofacial surgery 2002-08, Vol.31 (4), p.451-454 |
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container_title | International journal of oral and maxillofacial surgery |
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creator | Makino, T. Utsunomiya, T. Kamino, Y. Kobayashi, R. Fukumoto, M. Yamamoto, H. Nagura, H. |
description | Nerve sheath myxoma (NSM) is a benign peripheral nervous system tumour that rarely occurs in the oral cavity. Among 17 cases of oral NSM described in the literature (average patient age 33 years), only two, including the present case, have been reported in children. The present case occurring in an 8-year-old boy was therefore extremely rare. Histopathologically, the tumour was found as multinodules under the mucosal epithelium, and was composed of spindle- or stellate-shaped cells with a myxoid background that stained with alcian blue and toluidine blue. Immunohistochemically, the tumour cells were strongly positive for S-100 β protein and neuron-specific enolase. These results suggested that the tumour originated from Schwann cells. |
doi_str_mv | 10.1054/ijom.2001.0202 |
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Among 17 cases of oral NSM described in the literature (average patient age 33 years), only two, including the present case, have been reported in children. The present case occurring in an 8-year-old boy was therefore extremely rare. Histopathologically, the tumour was found as multinodules under the mucosal epithelium, and was composed of spindle- or stellate-shaped cells with a myxoid background that stained with alcian blue and toluidine blue. Immunohistochemically, the tumour cells were strongly positive for S-100 β protein and neuron-specific enolase. 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Among 17 cases of oral NSM described in the literature (average patient age 33 years), only two, including the present case, have been reported in children. The present case occurring in an 8-year-old boy was therefore extremely rare. Histopathologically, the tumour was found as multinodules under the mucosal epithelium, and was composed of spindle- or stellate-shaped cells with a myxoid background that stained with alcian blue and toluidine blue. Immunohistochemically, the tumour cells were strongly positive for S-100 β protein and neuron-specific enolase. These results suggested that the tumour originated from Schwann cells.</description><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Dentistry</subject><subject>histopathology</subject><subject>Humans</subject><subject>immunohistochemistry</subject><subject>Male</subject><subject>Medical sciences</subject><subject>nerve sheath myxoma</subject><subject>Neurology</subject><subject>Neurothekeoma - pathology</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>tongue</subject><subject>Tongue Neoplasms - pathology</subject><subject>Tumors</subject><subject>Tumors of the nervous system. Phacomatoses</subject><subject>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><issn>0901-5027</issn><issn>1399-0020</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10M9LwzAUwPEgipvTq0fpRU-2viRt0x5l-AuGXvQc0vTVZrTNTLrh_ntbVtjJ0yPwyePxJeSaQkQhiR_M2rYRA6ARMGAnZE55nocwPE7JHHKgYQJMzMiF92sAyHkmzsmMMp5SyJI5uX9Ht8PA16j6Omj3v7ZVga2Cvsagt933FgPTBSrQtWnKS3JWqcbj1TQX5Ov56XP5Gq4-Xt6Wj6tQxzztw7hIkiwpE0GZZmWV5gyznFcppjrRWBQAMdc0FzrjWVxRpoCmuhBVhkLzMmZ8Qe4OezfO_mzR97I1XmPTqA7t1kvBaCy4SAcYHaB21nuHldw40yq3lxTk2EeOfeTYR459hg830-Zt0WJ55FOQAdxOQHmtmsqpTht_dEO_NAc-uOzgcOiwM-ik1wY7jaVxqHtZWvPfDX9ADX7i</recordid><startdate>20020801</startdate><enddate>20020801</enddate><creator>Makino, T.</creator><creator>Utsunomiya, T.</creator><creator>Kamino, Y.</creator><creator>Kobayashi, R.</creator><creator>Fukumoto, M.</creator><creator>Yamamoto, H.</creator><creator>Nagura, H.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020801</creationdate><title>Nerve sheath myxoma of the tongue in a child</title><author>Makino, T. ; Utsunomiya, T. ; Kamino, Y. ; Kobayashi, R. ; Fukumoto, M. ; Yamamoto, H. ; Nagura, H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c436t-4b5585d5712c2df692e893f6e6c5cebb0043c197c8384f12a016cb7f8e7c3d423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Dentistry</topic><topic>histopathology</topic><topic>Humans</topic><topic>immunohistochemistry</topic><topic>Male</topic><topic>Medical sciences</topic><topic>nerve sheath myxoma</topic><topic>Neurology</topic><topic>Neurothekeoma - pathology</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>tongue</topic><topic>Tongue Neoplasms - pathology</topic><topic>Tumors</topic><topic>Tumors of the nervous system. Phacomatoses</topic><topic>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Makino, T.</creatorcontrib><creatorcontrib>Utsunomiya, T.</creatorcontrib><creatorcontrib>Kamino, Y.</creatorcontrib><creatorcontrib>Kobayashi, R.</creatorcontrib><creatorcontrib>Fukumoto, M.</creatorcontrib><creatorcontrib>Yamamoto, H.</creatorcontrib><creatorcontrib>Nagura, H.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of oral and maxillofacial surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Makino, T.</au><au>Utsunomiya, T.</au><au>Kamino, Y.</au><au>Kobayashi, R.</au><au>Fukumoto, M.</au><au>Yamamoto, H.</au><au>Nagura, H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nerve sheath myxoma of the tongue in a child</atitle><jtitle>International journal of oral and maxillofacial surgery</jtitle><addtitle>Int J Oral Maxillofac Surg</addtitle><date>2002-08-01</date><risdate>2002</risdate><volume>31</volume><issue>4</issue><spage>451</spage><epage>454</epage><pages>451-454</pages><issn>0901-5027</issn><eissn>1399-0020</eissn><coden>IJOSE9</coden><abstract>Nerve sheath myxoma (NSM) is a benign peripheral nervous system tumour that rarely occurs in the oral cavity. Among 17 cases of oral NSM described in the literature (average patient age 33 years), only two, including the present case, have been reported in children. The present case occurring in an 8-year-old boy was therefore extremely rare. Histopathologically, the tumour was found as multinodules under the mucosal epithelium, and was composed of spindle- or stellate-shaped cells with a myxoid background that stained with alcian blue and toluidine blue. Immunohistochemically, the tumour cells were strongly positive for S-100 β protein and neuron-specific enolase. These results suggested that the tumour originated from Schwann cells.</abstract><cop>Amsterdam</cop><pub>Elsevier Ltd</pub><pmid>12361085</pmid><doi>10.1054/ijom.2001.0202</doi><tpages>4</tpages></addata></record> |
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subjects | Biological and medical sciences Child Dentistry histopathology Humans immunohistochemistry Male Medical sciences nerve sheath myxoma Neurology Neurothekeoma - pathology Otorhinolaryngology. Stomatology tongue Tongue Neoplasms - pathology Tumors Tumors of the nervous system. Phacomatoses Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology |
title | Nerve sheath myxoma of the tongue in a child |
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