The Pharmacokinetic and Pharmacodynamic Characteristics of a Long-Acting Growth Hormone (GH) Preparation (Nutropin Depot) in GH-Deficient Adults

A pharmacokinetic-pharmacodynamic study of a long-acting GH [Nutropin Depot; somatropin (rDNA origin) for injectable suspension] was performed in 25 patients with adult GH deficiency. Single doses of 0.25 mg/kg and 0.5 mg/kg, based on ideal body weight, were administered sc. After either dose, serum...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2002-10, Vol.87 (10), p.4508-4514
Hauptverfasser:	Cook, D. M., Biller, B. M. K., Vance, M. L., Hoffman, A. R., Phillips, L. S., Ford, K. M., Benziger, D. P., Illeperuma, A., Blethen, S. L., Attie, K. M., Dao, L. N., Reimann, J. D., Fielder, P. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Blood Glucose - analysis Carrier Proteins - blood Delayed-Action Preparations Fasting Female Glycoproteins - blood Hormones. Endocrine system Human Growth Hormone - blood Human Growth Hormone - deficiency Human Growth Hormone - pharmacokinetics Human Growth Hormone - pharmacology Humans Insulin - blood Insulin-Like Growth Factor Binding Protein 3 - blood Insulin-Like Growth Factor I - analysis Kinetics Male Medical sciences Middle Aged Pharmacology. Drug treatments Sex Characteristics
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