Iontophoretic application of NMDA produces different types of excitatory responses in developing human cortical and caudate neurons

The effects of iontophoretically applied N- methyl- d-aspartate (NMDA) were assessed in human neocortical and caudate neurons. NMDA depolarized cell membranes, decreased input conductances and induced firing. The discharge patterns differed in the two areas studied. In neocortex, NMDA produced repet...

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Veröffentlicht in:	Neuroscience letters 1991-05, Vol.126 (2), p.167-171
Hauptverfasser:	Cepeda, Carlos, Peacock, Warwick, Levine, Michael S., Buchwald, Nathaniel A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Aging - physiology Biological and medical sciences Caudate Caudate Nucleus - cytology Caudate Nucleus - growth & development Caudate Nucleus - physiology Central nervous system Cerebral Cortex - cytology Cerebral Cortex - growth & development Cerebral Cortex - physiology Child Child, Preschool Development Electrophysiology Epilepsy Fundamental and applied biological sciences. Psychology Human Humans In Vitro Techniques Infant Iontophoresis N-Methylaspartate - pharmacology Neocortex Neurons - drug effects Neurons - physiology NMDA Vertebrates: nervous system and sense organs
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