Two distinct bombesin receptor subtypes are expressed and functional in human lung carcinoma cells

Bombesin-like peptides have been implicated as autocrine growth factors influencing the pathogenesis and progression of some human lung carcinoma cells. To determine the pharmacologic and structural properties of the bombesin receptors expressed in human lung carcinoma cells, cDNA clones encoding a...

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Veröffentlicht in:	The Journal of biological chemistry 1991-10, Vol.266 (28), p.18771-18779
Hauptverfasser:	CORJAY, M. H, DOBRZANSKI, D. J, WAY, J. M, VIALLET, J, SHAPIRA, H, WORLAND, P, SAUSVILLE, E. A, BATTEY, J. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Biological and medical sciences Bombesin - metabolism Calcium - metabolism Cell receptors Cell structures and functions Cloning, Molecular Deoxyribonucleotides Fundamental and applied biological sciences. Psychology Gastrin-Releasing Peptide genes Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors Humans Lung Neoplasms - metabolism Molecular and cellular biology Molecular Sequence Data Neurokinin B - analogs & derivatives Neurokinin B - genetics Neurokinin B - metabolism Peptides - genetics Peptides - metabolism Receptors, Bombesin Receptors, Neurotransmitter - metabolism Sequence Alignment Tumor Cells, Cultured
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