cDNA cloning of mouse NKR-P1 and genetic linkage with LY-49. Identification of a natural killer cell gene complex on mouse chromosome 6

NK cells lyse tumor cells and virally infected cells, but the molecular basis for this phenomenon has not been defined. A mAb specific for the rat cell surface molecule, NKR-P1, stimulates rat NK cell lytic activity and is reactive with all rat NK cells, suggesting that this molecule may play a sign...

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Veröffentlicht in:	The Journal of immunology (1950) 1991-11, Vol.147 (9), p.3229-3236
Hauptverfasser:	Yokoyama, WM, Ryan, JC, Hunter, JJ, Smith, HR, Stark, M, Seaman, WE
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antigens, Ly - genetics Antigens, Surface - genetics Asialoglycoprotein Receptor Base Sequence Biological and medical sciences cDNA Chromosome Mapping Cloning, Molecular DNA - genetics Fundamental and applied biological sciences. Psychology Genes Genes. Genome Genetic Linkage Killer Cells, Natural - physiology Lectins, C-Type Membrane Glycoproteins - genetics Mice Mice, Inbred C57BL Molecular and cellular biology Molecular genetics Molecular Sequence Data natural killer cells NK Cell Lectin-Like Receptor Subfamily B NKR-P1 antigen nucleotide sequence Polymorphism, Restriction Fragment Length predictions Receptors, Immunologic - genetics Sequence Alignment
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