Long-term treatment with Pilogel/beta-blocker in glaucoma patients
In a multicentre clinical trial thirteen patients with primary open angle glaucoma or ocular hypertension were followed during at least six months while selfinstilling Pilogel (once daily) and topical beta-blocker (twice daily). After six months of combination therapy there was an average decrease i...
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| Veröffentlicht in: | International ophthalmology 1991-07, Vol.15 (4), p.281-284 |
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| creator | Maas, S Ros, F E De Heer, L J De Keizer, R J |
| description | In a multicentre clinical trial thirteen patients with primary open angle glaucoma or ocular hypertension were followed during at least six months while selfinstilling Pilogel (once daily) and topical beta-blocker (twice daily). After six months of combination therapy there was an average decrease in intra-ocular pressure (IOP) of 33.6% 9.5 hours after Pilogel administration and an IOP decrease of 23.4% 22.5 hours after Pilogel administration. With topical beta-blocker alone, an average IOP decrease of 15% was measured. Throughout the study we observed in six patients (46.1%) a superficial punctate keratitis which mostly spontaneously cleared. We did not see any serious side-effects after six months of combination therapy. |
| doi_str_mv | 10.1007/BF00171032 |
| format | Article |
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| ispartof | International ophthalmology, 1991-07, Vol.15 (4), p.281-284 |
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| language | eng |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Adrenergic beta-Antagonists - therapeutic use Aged Aged, 80 and over Drug Administration Schedule Drug Therapy, Combination Female Gels Glaucoma, Open-Angle - drug therapy Humans Intraocular Pressure - drug effects Longitudinal Studies Male Middle Aged Ocular Hypertension - drug therapy Pilocarpine - therapeutic use Pupil - drug effects Refraction, Ocular Visual Fields - drug effects |
| title | Long-term treatment with Pilogel/beta-blocker in glaucoma patients |
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