Effectiveness of Pharmacist Care for Patients With Reactive Airways Disease: A Randomized Controlled Trial

CONTEXT It is not known whether patient outcomes are enhanced by effective pharmacist-patient interactions. OBJECTIVE To assess the effectiveness of a pharmaceutical care program for patients with asthma or chronic obstructive pulmonary disease (COPD). DESIGN, SETTING, AND PARTICIPANTS Randomized co...

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Veröffentlicht in:JAMA : the journal of the American Medical Association 2002-10, Vol.288 (13), p.1594-1602
Hauptverfasser: Weinberger, Morris, Murray, Michael D, Marrero, David G, Brewer, Nancy, Lykens, Michael, Harris, Lisa E, Seshadri, Roopa, Caffrey, Helena, Roesner, J. Franklin, Smith, Faye, Newell, A. Jeffrey, Collins, Joyce C, McDonald, Clement J, Tierney, William M
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container_issue 13
container_start_page 1594
container_title JAMA : the journal of the American Medical Association
container_volume 288
creator Weinberger, Morris
Murray, Michael D
Marrero, David G
Brewer, Nancy
Lykens, Michael
Harris, Lisa E
Seshadri, Roopa
Caffrey, Helena
Roesner, J. Franklin
Smith, Faye
Newell, A. Jeffrey
Collins, Joyce C
McDonald, Clement J
Tierney, William M
description CONTEXT It is not known whether patient outcomes are enhanced by effective pharmacist-patient interactions. OBJECTIVE To assess the effectiveness of a pharmaceutical care program for patients with asthma or chronic obstructive pulmonary disease (COPD). DESIGN, SETTING, AND PARTICIPANTS Randomized controlled trial conducted at 36 community drugstores in Indianapolis, Ind. We enrolled 1113 participants with active COPD or asthma from July 1998 to December 1999. Outcomes were assessed in 947 (85.1%) participants at 6 months and 898 (80.7%) at 12 months. INTERVENTIONS The pharmaceutical care program (n = 447) provided pharmacists with recent patient-specific clinical data (peak expiratory flow rates [PEFRs], emergency department [ED] visits, hospitalizations, and medication compliance), training, customized patient educational materials, and resources to facilitate program implementation. The PEFR monitoring control group (n = 363) received a peak flow meter, instructions about its use, and monthly calls to elicit PEFRs. However, PEFR data were not provided to the pharmacist. Patients in the usual care group (n = 303) received neither peak flow meters nor instructions in their use; during monthly telephone interviews, PEFR rates were not elicited. Pharmacists in both control groups had a training session but received no components of the pharmaceutical care intervention. MAIN OUTCOME MEASURES Peak expiratory flow rates, breathing-related ED or hospital visits, health-related quality of life (HRQOL), medication compliance, and patient satisfaction. RESULTS At 12 months, patients receiving pharmaceutical care had significantly higher peak flow rates than the usual care group (P = .02) but not than PEFR monitoring controls (P = .28). There were no significant between-group differences in medication compliance or HRQOL. Asthma patients receiving pharmaceutical care had significantly more breathing-related ED or hospital visits than the usual care group (odds ratio, 2.16; 95% confidence interval, 1.76-2.63; P
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Franklin ; Smith, Faye ; Newell, A. Jeffrey ; Collins, Joyce C ; McDonald, Clement J ; Tierney, William M</creator><creatorcontrib>Weinberger, Morris ; Murray, Michael D ; Marrero, David G ; Brewer, Nancy ; Lykens, Michael ; Harris, Lisa E ; Seshadri, Roopa ; Caffrey, Helena ; Roesner, J. Franklin ; Smith, Faye ; Newell, A. Jeffrey ; Collins, Joyce C ; McDonald, Clement J ; Tierney, William M</creatorcontrib><description>CONTEXT It is not known whether patient outcomes are enhanced by effective pharmacist-patient interactions. OBJECTIVE To assess the effectiveness of a pharmaceutical care program for patients with asthma or chronic obstructive pulmonary disease (COPD). DESIGN, SETTING, AND PARTICIPANTS Randomized controlled trial conducted at 36 community drugstores in Indianapolis, Ind. We enrolled 1113 participants with active COPD or asthma from July 1998 to December 1999. Outcomes were assessed in 947 (85.1%) participants at 6 months and 898 (80.7%) at 12 months. INTERVENTIONS The pharmaceutical care program (n = 447) provided pharmacists with recent patient-specific clinical data (peak expiratory flow rates [PEFRs], emergency department [ED] visits, hospitalizations, and medication compliance), training, customized patient educational materials, and resources to facilitate program implementation. The PEFR monitoring control group (n = 363) received a peak flow meter, instructions about its use, and monthly calls to elicit PEFRs. However, PEFR data were not provided to the pharmacist. Patients in the usual care group (n = 303) received neither peak flow meters nor instructions in their use; during monthly telephone interviews, PEFR rates were not elicited. Pharmacists in both control groups had a training session but received no components of the pharmaceutical care intervention. MAIN OUTCOME MEASURES Peak expiratory flow rates, breathing-related ED or hospital visits, health-related quality of life (HRQOL), medication compliance, and patient satisfaction. RESULTS At 12 months, patients receiving pharmaceutical care had significantly higher peak flow rates than the usual care group (P = .02) but not than PEFR monitoring controls (P = .28). There were no significant between-group differences in medication compliance or HRQOL. Asthma patients receiving pharmaceutical care had significantly more breathing-related ED or hospital visits than the usual care group (odds ratio, 2.16; 95% confidence interval, 1.76-2.63; P&lt;.001). Patients receiving pharmaceutical care were more satisfied with their pharmacist than the usual care group (P = .03) and the PEFR monitoring group (P = .001) and were more satisfied with their health care than the usual care group at 6 months only (P = .01). Despite ample opportunities to implement the program, pharmacists accessed patient-specific data only about half of the time and documented actions about half of the time that records were accessed. CONCLUSIONS This pharmaceutical care program increased patients' PEFRs compared with usual care but provided little benefit compared with peak flow monitoring alone. Pharmaceutical care increased patient satisfaction but also increased the amount of breathing-related medical care sought.</description><identifier>ISSN: 0098-7484</identifier><identifier>EISSN: 1538-3598</identifier><identifier>DOI: 10.1001/jama.288.13.1594</identifier><identifier>PMID: 12350190</identifier><identifier>CODEN: JAMAAP</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Adult ; Ambulatory Care Facilities ; Asthma - therapy ; Biological and medical sciences ; Clinical outcomes ; Clinical trials ; Emergencies ; Female ; Humans ; Indiana ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical sciences ; Middle Aged ; Outcome Assessment (Health Care) ; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques ; Patient Compliance ; Patient education ; Patient Satisfaction ; Peak Expiratory Flow Rate ; Pharmacies ; Pharmacists ; Pulmonary Disease, Chronic Obstructive - therapy ; Respiratory diseases ; Respiratory system ; Sickness Impact Profile</subject><ispartof>JAMA : the journal of the American Medical Association, 2002-10, Vol.288 (13), p.1594-1602</ispartof><rights>2002 INIST-CNRS</rights><rights>Copyright American Medical Association Oct 2, 2002</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jamanetwork.com/journals/jama/articlepdf/10.1001/jama.288.13.1594$$EPDF$$P50$$Gama$$H</linktopdf><linktohtml>$$Uhttps://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.288.13.1594$$EHTML$$P50$$Gama$$H</linktohtml><link.rule.ids>64,314,776,780,3327,27901,27902,76231,76234</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=13971442$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12350190$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Weinberger, Morris</creatorcontrib><creatorcontrib>Murray, Michael D</creatorcontrib><creatorcontrib>Marrero, David G</creatorcontrib><creatorcontrib>Brewer, Nancy</creatorcontrib><creatorcontrib>Lykens, Michael</creatorcontrib><creatorcontrib>Harris, Lisa E</creatorcontrib><creatorcontrib>Seshadri, Roopa</creatorcontrib><creatorcontrib>Caffrey, Helena</creatorcontrib><creatorcontrib>Roesner, J. Franklin</creatorcontrib><creatorcontrib>Smith, Faye</creatorcontrib><creatorcontrib>Newell, A. Jeffrey</creatorcontrib><creatorcontrib>Collins, Joyce C</creatorcontrib><creatorcontrib>McDonald, Clement J</creatorcontrib><creatorcontrib>Tierney, William M</creatorcontrib><title>Effectiveness of Pharmacist Care for Patients With Reactive Airways Disease: A Randomized Controlled Trial</title><title>JAMA : the journal of the American Medical Association</title><addtitle>JAMA</addtitle><description>CONTEXT It is not known whether patient outcomes are enhanced by effective pharmacist-patient interactions. OBJECTIVE To assess the effectiveness of a pharmaceutical care program for patients with asthma or chronic obstructive pulmonary disease (COPD). DESIGN, SETTING, AND PARTICIPANTS Randomized controlled trial conducted at 36 community drugstores in Indianapolis, Ind. We enrolled 1113 participants with active COPD or asthma from July 1998 to December 1999. Outcomes were assessed in 947 (85.1%) participants at 6 months and 898 (80.7%) at 12 months. INTERVENTIONS The pharmaceutical care program (n = 447) provided pharmacists with recent patient-specific clinical data (peak expiratory flow rates [PEFRs], emergency department [ED] visits, hospitalizations, and medication compliance), training, customized patient educational materials, and resources to facilitate program implementation. The PEFR monitoring control group (n = 363) received a peak flow meter, instructions about its use, and monthly calls to elicit PEFRs. However, PEFR data were not provided to the pharmacist. Patients in the usual care group (n = 303) received neither peak flow meters nor instructions in their use; during monthly telephone interviews, PEFR rates were not elicited. Pharmacists in both control groups had a training session but received no components of the pharmaceutical care intervention. MAIN OUTCOME MEASURES Peak expiratory flow rates, breathing-related ED or hospital visits, health-related quality of life (HRQOL), medication compliance, and patient satisfaction. RESULTS At 12 months, patients receiving pharmaceutical care had significantly higher peak flow rates than the usual care group (P = .02) but not than PEFR monitoring controls (P = .28). There were no significant between-group differences in medication compliance or HRQOL. Asthma patients receiving pharmaceutical care had significantly more breathing-related ED or hospital visits than the usual care group (odds ratio, 2.16; 95% confidence interval, 1.76-2.63; P&lt;.001). Patients receiving pharmaceutical care were more satisfied with their pharmacist than the usual care group (P = .03) and the PEFR monitoring group (P = .001) and were more satisfied with their health care than the usual care group at 6 months only (P = .01). Despite ample opportunities to implement the program, pharmacists accessed patient-specific data only about half of the time and documented actions about half of the time that records were accessed. CONCLUSIONS This pharmaceutical care program increased patients' PEFRs compared with usual care but provided little benefit compared with peak flow monitoring alone. Pharmaceutical care increased patient satisfaction but also increased the amount of breathing-related medical care sought.</description><subject>Adult</subject><subject>Ambulatory Care Facilities</subject><subject>Asthma - therapy</subject><subject>Biological and medical sciences</subject><subject>Clinical outcomes</subject><subject>Clinical trials</subject><subject>Emergencies</subject><subject>Female</subject><subject>Humans</subject><subject>Indiana</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Outcome Assessment (Health Care)</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</subject><subject>Patient Compliance</subject><subject>Patient education</subject><subject>Patient Satisfaction</subject><subject>Peak Expiratory Flow Rate</subject><subject>Pharmacies</subject><subject>Pharmacists</subject><subject>Pulmonary Disease, Chronic Obstructive - therapy</subject><subject>Respiratory diseases</subject><subject>Respiratory system</subject><subject>Sickness Impact Profile</subject><issn>0098-7484</issn><issn>1538-3598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpd0d1LHDEQAPBQlHo9-25fShDatz3ztZvEt-N6rYLgcSh9XOY2E8yxH5rsVfSvb9ATwbxMYH4zDDOEnHA244zxsy10MBPGzLic8dKqT2TCS2kKWVpzQCaMWVNoZdQR-ZLSluXHpf5MjriQJeOWTch26T02Y_iHPaZEB09XdxA7aEIa6QIiUj9EuoIxYD8m-jeMd3SN8FJB5yE-wlOiv0JCSHhO53QNvRu68IyOLoZ-jEPb5u9NDNAek0MPbcKv-zglt7-XN4uL4ur6z-ViflWAMGIspALnpd0A6g1zlW8scscEGCUqrwGVAuvEptJQWaFUqVylK2WVBI3OMiOn5Odr3_s4POwwjXUXUoNtCz0Ou1RrwWVprMzw9APcDrvY59lqwbORgquMvu_RbtOhq-9j6CA-1W8rzODHHkBqoPUR-ry8dyet5kqJ7L69unyz96wtpZLyP62TiB4</recordid><startdate>20021002</startdate><enddate>20021002</enddate><creator>Weinberger, Morris</creator><creator>Murray, Michael D</creator><creator>Marrero, David G</creator><creator>Brewer, Nancy</creator><creator>Lykens, Michael</creator><creator>Harris, Lisa E</creator><creator>Seshadri, Roopa</creator><creator>Caffrey, Helena</creator><creator>Roesner, J. Franklin</creator><creator>Smith, Faye</creator><creator>Newell, A. Jeffrey</creator><creator>Collins, Joyce C</creator><creator>McDonald, Clement J</creator><creator>Tierney, William M</creator><general>American Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QL</scope><scope>7QP</scope><scope>7TK</scope><scope>7TS</scope><scope>7U7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20021002</creationdate><title>Effectiveness of Pharmacist Care for Patients With Reactive Airways Disease: A Randomized Controlled Trial</title><author>Weinberger, Morris ; Murray, Michael D ; Marrero, David G ; Brewer, Nancy ; Lykens, Michael ; Harris, Lisa E ; Seshadri, Roopa ; Caffrey, Helena ; Roesner, J. 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Miscellaneous investigative techniques</topic><topic>Patient Compliance</topic><topic>Patient education</topic><topic>Patient Satisfaction</topic><topic>Peak Expiratory Flow Rate</topic><topic>Pharmacies</topic><topic>Pharmacists</topic><topic>Pulmonary Disease, Chronic Obstructive - therapy</topic><topic>Respiratory diseases</topic><topic>Respiratory system</topic><topic>Sickness Impact Profile</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weinberger, Morris</creatorcontrib><creatorcontrib>Murray, Michael D</creatorcontrib><creatorcontrib>Marrero, David G</creatorcontrib><creatorcontrib>Brewer, Nancy</creatorcontrib><creatorcontrib>Lykens, Michael</creatorcontrib><creatorcontrib>Harris, Lisa E</creatorcontrib><creatorcontrib>Seshadri, Roopa</creatorcontrib><creatorcontrib>Caffrey, Helena</creatorcontrib><creatorcontrib>Roesner, J. Franklin</creatorcontrib><creatorcontrib>Smith, Faye</creatorcontrib><creatorcontrib>Newell, A. 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DESIGN, SETTING, AND PARTICIPANTS Randomized controlled trial conducted at 36 community drugstores in Indianapolis, Ind. We enrolled 1113 participants with active COPD or asthma from July 1998 to December 1999. Outcomes were assessed in 947 (85.1%) participants at 6 months and 898 (80.7%) at 12 months. INTERVENTIONS The pharmaceutical care program (n = 447) provided pharmacists with recent patient-specific clinical data (peak expiratory flow rates [PEFRs], emergency department [ED] visits, hospitalizations, and medication compliance), training, customized patient educational materials, and resources to facilitate program implementation. The PEFR monitoring control group (n = 363) received a peak flow meter, instructions about its use, and monthly calls to elicit PEFRs. However, PEFR data were not provided to the pharmacist. Patients in the usual care group (n = 303) received neither peak flow meters nor instructions in their use; during monthly telephone interviews, PEFR rates were not elicited. Pharmacists in both control groups had a training session but received no components of the pharmaceutical care intervention. MAIN OUTCOME MEASURES Peak expiratory flow rates, breathing-related ED or hospital visits, health-related quality of life (HRQOL), medication compliance, and patient satisfaction. RESULTS At 12 months, patients receiving pharmaceutical care had significantly higher peak flow rates than the usual care group (P = .02) but not than PEFR monitoring controls (P = .28). There were no significant between-group differences in medication compliance or HRQOL. Asthma patients receiving pharmaceutical care had significantly more breathing-related ED or hospital visits than the usual care group (odds ratio, 2.16; 95% confidence interval, 1.76-2.63; P&lt;.001). Patients receiving pharmaceutical care were more satisfied with their pharmacist than the usual care group (P = .03) and the PEFR monitoring group (P = .001) and were more satisfied with their health care than the usual care group at 6 months only (P = .01). Despite ample opportunities to implement the program, pharmacists accessed patient-specific data only about half of the time and documented actions about half of the time that records were accessed. CONCLUSIONS This pharmaceutical care program increased patients' PEFRs compared with usual care but provided little benefit compared with peak flow monitoring alone. Pharmaceutical care increased patient satisfaction but also increased the amount of breathing-related medical care sought.</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>12350190</pmid><doi>10.1001/jama.288.13.1594</doi><tpages>9</tpages></addata></record>
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subjects Adult
Ambulatory Care Facilities
Asthma - therapy
Biological and medical sciences
Clinical outcomes
Clinical trials
Emergencies
Female
Humans
Indiana
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Outcome Assessment (Health Care)
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Patient Compliance
Patient education
Patient Satisfaction
Peak Expiratory Flow Rate
Pharmacies
Pharmacists
Pulmonary Disease, Chronic Obstructive - therapy
Respiratory diseases
Respiratory system
Sickness Impact Profile
title Effectiveness of Pharmacist Care for Patients With Reactive Airways Disease: A Randomized Controlled Trial
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