Metabotropic glutamate receptor involvement in phosphoinositide hydrolysis stimulation by an endogenous Na +, K +-ATPase inhibitor and ouabain in neonatal rat brain

The mechanism of action of an endogenous Na +, K +-ATPase inhibitor, termed endobain E, on phosphoinositide hydrolysis was studied in neonatal rat brain cortex and compared with that of ouabain. Lack of additivity for endobain E and glutamate paired stimulation on inositol phosphates accumulation su...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research. Developmental brain research 2002-10, Vol.138 (2), p.167-175
Hauptverfasser:	Calviño, M.A, Peña, C, Rodrı́guez de Lores Arnaiz, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn - physiology Brain - drug effects Brain - enzymology Cadmium - pharmacology Cerebral Cortex - drug effects Cerebral Cortex - enzymology Enzyme Inhibitors - pharmacology Female Hydrolysis Indicators and Reagents Inositol - metabolism Male Metabotropic glutamate receptor Muscarinic Antagonists - pharmacology Na +, K +-ATPase Neonatal brain cortex Ouabain - analogs & derivatives Ouabain - metabolism Ouabain - pharmacology Ouabain-like substance Phosphatidylinositols - metabolism Phosphoinositide hydrolysis Rats Rats, Wistar Receptor, Metabotropic Glutamate 5 Receptors, Metabotropic Glutamate - metabolism Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!