Expression of the nuclear RING finger protein SNURF/RNF4 during rat testis development suggests a role in spermatid maturation

A small nuclear RING finger protein, termed SNURF (or RNF4), is a coregulator of androgen receptor-dependent transcription. To elucidate the physiological role of SNURF in vivo, cell type-specific localization and changes in SNURF mRNA and protein accumulation were followed during testicular develop...

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Veröffentlicht in:	Mechanisms of development 2002-10, Vol.118 (1), p.247-253
Hauptverfasser:	Yan, Wei, Hirvonen-Santti, Sirpa J, Palvimo, Jorma J, Toppari, Jorma, Jänne, Olli A
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen receptor Animals Base Sequence Blotting, Northern Chromatin - metabolism Coactivator Coregulatory protein DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics Immunoblotting Immunohistochemistry In Situ Hybridization Male Molecular Sequence Data Nuclear Proteins - biosynthesis Nuclear Proteins - genetics Rats Rats, Sprague-Dawley RNA - metabolism RNA, Messenger - metabolism RNF4 SNURF Spermatid Spermatids - physiology Spermatocytes - metabolism Spermatogenesis Testis - embryology Testosterone Time Factors Transcription Factors - biosynthesis Transcription Factors - genetics Zinc Fingers
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