Comparable bioavailability of two esophago-gastric protective formulations containing pamidronate. A cross-over trial in healthy young adults

The net absorbable amount of pamidronate (APD), according to AUC values assessed in blood, in the customary dose interval of 24 hours, was found to be similar in 8 healthy young volunteers, who received single doses of 3 capsules of 100 mg APD (AUC0-24 = 510.3 +/- 91.5 micrograms/L x h-1) and 2 tabl...

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Veröffentlicht in:	Medicina (Buenos Aires) 2002, Vol.62 (4), p.317-322
Hauptverfasser:	Roldán, Emilio J A, Quattrocchi, Oscar, Zanchetta, Jose, Plotkin, Horacio, Araujo, Graciela, Piccinni, Enrique
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Anti-Inflammatory Agents - pharmacokinetics Biological Availability Cross-Over Studies Diphosphonates - pharmacokinetics Female Gastrointestinal Agents - pharmacokinetics Humans Male Protective Agents - pharmacokinetics
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