Progress and challenges in the pathological diagnosis of myocarditis
The pathological diagnosis of myocarditis rests on well-described histopathological criteria. Appreciation for the disease-specific sensitivity of the endomyocardial biopsy, as well as the phenotypical and functional nature of inflammatory infiltrates, will enhance the clinical utility of the biopsy...
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Veröffentlicht in: | European heart journal 1991-08, Vol.12 (suppl-D), p.18-21 |
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container_issue | suppl-D |
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container_title | European heart journal |
container_volume | 12 |
creator | McManus, B. M. Chow, L. H. Radio, S. J. Tracy, S. M. Beck, M. A. Chapman, N. M. Klingel, K. Kandolf, R. |
description | The pathological diagnosis of myocarditis rests on well-described histopathological criteria. Appreciation for the disease-specific sensitivity of the endomyocardial biopsy, as well as the phenotypical and functional nature of inflammatory infiltrates, will enhance the clinical utility of the biopsy technique. New information regarding the role of enteroviruses in immunological sensitization and the study of enteroviruses in murine models and human patients are fostering new perspectives and routes of investigation of appropriate therapeutic interventions for myocarditis. |
doi_str_mv | 10.1093/eurheartj/12.suppl_D.18 |
format | Article |
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M. ; Chow, L. H. ; Radio, S. J. ; Tracy, S. M. ; Beck, M. A. ; Chapman, N. M. ; Klingel, K. ; Kandolf, R.</creator><creatorcontrib>McManus, B. M. ; Chow, L. H. ; Radio, S. J. ; Tracy, S. M. ; Beck, M. A. ; Chapman, N. M. ; Klingel, K. ; Kandolf, R.</creatorcontrib><description>The pathological diagnosis of myocarditis rests on well-described histopathological criteria. Appreciation for the disease-specific sensitivity of the endomyocardial biopsy, as well as the phenotypical and functional nature of inflammatory infiltrates, will enhance the clinical utility of the biopsy technique. New information regarding the role of enteroviruses in immunological sensitization and the study of enteroviruses in murine models and human patients are fostering new perspectives and routes of investigation of appropriate therapeutic interventions for myocarditis.</description><identifier>ISSN: 0195-668X</identifier><identifier>EISSN: 1522-9645</identifier><identifier>DOI: 10.1093/eurheartj/12.suppl_D.18</identifier><identifier>PMID: 1655447</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Animals ; Biological and medical sciences ; Cardiology. 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M.</creatorcontrib><creatorcontrib>Chow, L. H.</creatorcontrib><creatorcontrib>Radio, S. J.</creatorcontrib><creatorcontrib>Tracy, S. M.</creatorcontrib><creatorcontrib>Beck, M. A.</creatorcontrib><creatorcontrib>Chapman, N. M.</creatorcontrib><creatorcontrib>Klingel, K.</creatorcontrib><creatorcontrib>Kandolf, R.</creatorcontrib><title>Progress and challenges in the pathological diagnosis of myocarditis</title><title>European heart journal</title><addtitle>Eur Heart J</addtitle><description>The pathological diagnosis of myocarditis rests on well-described histopathological criteria. Appreciation for the disease-specific sensitivity of the endomyocardial biopsy, as well as the phenotypical and functional nature of inflammatory infiltrates, will enhance the clinical utility of the biopsy technique. New information regarding the role of enteroviruses in immunological sensitization and the study of enteroviruses in murine models and human patients are fostering new perspectives and routes of investigation of appropriate therapeutic interventions for myocarditis.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>cardiomyopathy</subject><subject>Cells, Cultured</subject><subject>Coxsackievirus Infections - pathology</subject><subject>cytolytic assays</subject><subject>Disease Models, Animal</subject><subject>Endocardium - pathology</subject><subject>enterovirus</subject><subject>Enterovirus B, Human</subject><subject>Enterovirus Infections - pathology</subject><subject>Heart</subject><subject>Humans</subject><subject>immunohistochemistry</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>murine model</subject><subject>myocarditis</subject><subject>Myocarditis - microbiology</subject><subject>Myocarditis - pathology</subject><subject>Myocarditis. 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subjects | Animals Biological and medical sciences Cardiology. Vascular system cardiomyopathy Cells, Cultured Coxsackievirus Infections - pathology cytolytic assays Disease Models, Animal Endocardium - pathology enterovirus Enterovirus B, Human Enterovirus Infections - pathology Heart Humans immunohistochemistry Medical sciences Mice murine model myocarditis Myocarditis - microbiology Myocarditis - pathology Myocarditis. Cardiomyopathies Myocardium - pathology Pathological diagnosis Sensitivity and Specificity |
title | Progress and challenges in the pathological diagnosis of myocarditis |
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