Progress and challenges in the pathological diagnosis of myocarditis

The pathological diagnosis of myocarditis rests on well-described histopathological criteria. Appreciation for the disease-specific sensitivity of the endomyocardial biopsy, as well as the phenotypical and functional nature of inflammatory infiltrates, will enhance the clinical utility of the biopsy...

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Veröffentlicht in:European heart journal 1991-08, Vol.12 (suppl-D), p.18-21
Hauptverfasser: McManus, B. M., Chow, L. H., Radio, S. J., Tracy, S. M., Beck, M. A., Chapman, N. M., Klingel, K., Kandolf, R.
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container_end_page 21
container_issue suppl-D
container_start_page 18
container_title European heart journal
container_volume 12
creator McManus, B. M.
Chow, L. H.
Radio, S. J.
Tracy, S. M.
Beck, M. A.
Chapman, N. M.
Klingel, K.
Kandolf, R.
description The pathological diagnosis of myocarditis rests on well-described histopathological criteria. Appreciation for the disease-specific sensitivity of the endomyocardial biopsy, as well as the phenotypical and functional nature of inflammatory infiltrates, will enhance the clinical utility of the biopsy technique. New information regarding the role of enteroviruses in immunological sensitization and the study of enteroviruses in murine models and human patients are fostering new perspectives and routes of investigation of appropriate therapeutic interventions for myocarditis.
doi_str_mv 10.1093/eurheartj/12.suppl_D.18
format Article
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identifier ISSN: 0195-668X
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source MEDLINE; Oxford University Press Journals Digital Archive Legacy
subjects Animals
Biological and medical sciences
Cardiology. Vascular system
cardiomyopathy
Cells, Cultured
Coxsackievirus Infections - pathology
cytolytic assays
Disease Models, Animal
Endocardium - pathology
enterovirus
Enterovirus B, Human
Enterovirus Infections - pathology
Heart
Humans
immunohistochemistry
Medical sciences
Mice
murine model
myocarditis
Myocarditis - microbiology
Myocarditis - pathology
Myocarditis. Cardiomyopathies
Myocardium - pathology
Pathological diagnosis
Sensitivity and Specificity
title Progress and challenges in the pathological diagnosis of myocarditis
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