The effects of lidocaine and adrenergic agonists on rat sciatic nerve and skeletal muscle blood flow in vivo

It has been proposed that epinephrine prolongs lidocaine nerve blockade duration by exerting a local vasoconstrictive effect on tissues at the injection site, slowing lidocaine's local clearance. However, previous studies have failed to demonstrate consistent effects of lidocaine and epinephrin...

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Veröffentlicht in:	Anesthesia and analgesia 2002-10, Vol.95 (4), p.1080-1086
Hauptverfasser:	PALMER, Greta M, CAIRNS, Brian E, BERKES, Steven L, DUNNING, Patricia S, TAYLOR, George A, BERDE, Charles B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic Agonists - pharmacology Anesthetics, Local - pharmacology Anesthetics. Neuromuscular blocking agents Animals Biological and medical sciences Cardiovascular system Epinephrine - pharmacology Lidocaine - pharmacology Male Medical sciences Microspheres Miscellaneous Muscle, Skeletal - blood supply Muscle, Skeletal - drug effects Neuropharmacology Pharmacology. Drug treatments Phenylephrine - pharmacology Rats Rats, Sprague-Dawley Regional Blood Flow - drug effects Sciatic Nerve - blood supply Sciatic Nerve - drug effects
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