Novel Mycobacterium tuberculosis anti-sigma factor antagonists control sigmaF activity by distinct mechanisms

The aetiological agent of tuberculosis, Mycobacterium tuberculosis, encodes 13 sigma factors, as well as several putative anti-, and anti-anti- sigma factors. Here we show that a sigma factor that has been previously shown to be involved in virulence and persistence processes, sigmaF, can be specifi...

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Veröffentlicht in:	Molecular microbiology 2002-09, Vol.45 (6), p.1527-1540
Hauptverfasser:	Beaucher, Jocelyn, Rodrigue, Sébastien, Jacques, Pierre-Etienne, Smith, Issar, Brzezinski, Ryszard, Gaudreau, Luc
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacterial Proteins - genetics Bacterial Proteins - metabolism Gene Expression Regulation, Bacterial Molecular Sequence Data Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - metabolism Oxidation-Reduction Phosphorylation Promoter Regions, Genetic Sigma Factor - antagonists & inhibitors Sigma Factor - genetics Sigma Factor - metabolism Transcription, Genetic
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