Characterization of Expression of a Functionally Conserved Helicobacter pylori Methyltransferase-Encoding Gene within Inflamed Mucosa and during In Vitro Growth

Methylation of bacterial DNA can regulate microbial growth and virulence. Expression of hpyIM a conserved methyltransferase of the gastric pathogen Helicobacter pylori was quantitated in gastric biopsy specimens from 41 H. pylori–infected patients and during growth in vitro, by quantitative reverse...

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Veröffentlicht in:	The Journal of infectious diseases 2002-10, Vol.186 (8), p.1186-1189
Hauptverfasser:	Takeuchi, Hiroaki, Israel, Dawn A., Miller, Geraldine G., Donahue, John P., Krishna, Uma, Gaus, Kristin, Peek, Richard M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial diseases Bacterial diseases of the digestive system and abdomen Biological and medical sciences Biopsies Concise Communications Digestive system diseases DNA Electrical phases Gastric Mucosa - microbiology Gastric Mucosa - pathology Gene Expression Regulation, Bacterial Genes, Bacterial - genetics Helicobacter Infections - microbiology Helicobacter Infections - pathology Helicobacter pylori Helicobacter pylori - enzymology Helicobacter pylori - genetics Helicobacter pylori - growth & development Helicobacter pylori - ultrastructure Human bacterial diseases Humans Immunoblotting Infectious diseases Inflammation - microbiology Medical sciences Methylation Methyltransferases - biosynthesis Methyltransferases - genetics Methyltransferases - metabolism Pathology Reverse Transcriptase Polymerase Chain Reaction RNA RNA, Bacterial - analysis RNA, Bacterial - genetics Steepest descent method
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