Changing concepts in the management of vulvar cancer
Vulvar carcinoma varies widely in its clinical presentations and prognosis. The reviewed literature outlines the achievements of conventional surgery, radiation, or chemoradiation therapy in its management. Currently therapeutic concepts are evolving. New treatment strategies replacing the uniform u...
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| Veröffentlicht in: | Gynecologic Oncology 1991-07, Vol.42 (1), p.9-21 |
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| container_title | Gynecologic Oncology |
| container_volume | 42 |
| creator | Thomas, G.M. Dembo, A.J. Bryson, S.C.P. Osborne, R. DePetrillo, A.D. |
| description | Vulvar carcinoma varies widely in its clinical presentations and prognosis. The reviewed literature outlines the achievements of conventional surgery, radiation, or chemoradiation therapy in its management. Currently therapeutic concepts are evolving. New treatment strategies replacing the uniform use of radical vulvectomy and bilateral groin dissection are proposed. These strategies are tailored to the clinical and pathological disease extent and location and integrate the possible therapeutic advantages of both surgery and chemoradiation. The testing and use of the proposed multimodality therapy protocols require the expertise of gynecologic, radiation, and medical oncologists. This approach should lead to improved anatomic and functional preservation in early disease and improved locoregional in advanced disease. |
| doi_str_mv | 10.1016/0090-8258(91)90223-R |
| format | Article |
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The reviewed literature outlines the achievements of conventional surgery, radiation, or chemoradiation therapy in its management. Currently therapeutic concepts are evolving. New treatment strategies replacing the uniform use of radical vulvectomy and bilateral groin dissection are proposed. These strategies are tailored to the clinical and pathological disease extent and location and integrate the possible therapeutic advantages of both surgery and chemoradiation. The testing and use of the proposed multimodality therapy protocols require the expertise of gynecologic, radiation, and medical oncologists. 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Obstetrics</topic><topic>Humans</topic><topic>Lymph Nodes - surgery</topic><topic>Medical sciences</topic><topic>Pelvis</topic><topic>Terminology as Topic</topic><topic>Tumors</topic><topic>Vulva - surgery</topic><topic>Vulvar Neoplasms - radiotherapy</topic><topic>Vulvar Neoplasms - surgery</topic><topic>Vulvar Neoplasms - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thomas, G.M.</creatorcontrib><creatorcontrib>Dembo, A.J.</creatorcontrib><creatorcontrib>Bryson, S.C.P.</creatorcontrib><creatorcontrib>Osborne, R.</creatorcontrib><creatorcontrib>DePetrillo, A.D.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Gynecologic Oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thomas, G.M.</au><au>Dembo, A.J.</au><au>Bryson, S.C.P.</au><au>Osborne, R.</au><au>DePetrillo, A.D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Changing concepts in the management of vulvar cancer</atitle><jtitle>Gynecologic Oncology</jtitle><addtitle>Gynecol Oncol</addtitle><date>1991-07-01</date><risdate>1991</risdate><volume>42</volume><issue>1</issue><spage>9</spage><epage>21</epage><pages>9-21</pages><issn>0090-8258</issn><eissn>1095-6859</eissn><coden>GYNOA3</coden><abstract>Vulvar carcinoma varies widely in its clinical presentations and prognosis. 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| ispartof | Gynecologic Oncology, 1991-07, Vol.42 (1), p.9-21 |
| issn | 0090-8258 1095-6859 |
| language | eng |
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| source | MEDLINE; ScienceDirect Freedom Collection (Elsevier) |
| subjects | Algorithms Antineoplastic Agents - therapeutic use Biological and medical sciences Female Female genital diseases Forecasting Groin Gynecology. Andrology. Obstetrics Humans Lymph Nodes - surgery Medical sciences Pelvis Terminology as Topic Tumors Vulva - surgery Vulvar Neoplasms - radiotherapy Vulvar Neoplasms - surgery Vulvar Neoplasms - therapy |
| title | Changing concepts in the management of vulvar cancer |
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