IN VITRO AUTORADIOGRAPHIC ENDOTHELIN-1 BINDING SITES AND SARAFOTOXIN S6B BINDING SITES IN RAT TISSUES

SUMMARY 1. The distribution of binding sites for [125I]‐labelled endothelin‐1 ([125I]‐ET‐1) and [125I]‐labelled sarafotoxin S6B ([125I]‐SRT) was visualized in rat tissues using in vitro autoradiography. 2. A high density of endothelin‐1 (ET‐1) binding was found in the heart. In the kidney, ET‐1 bind...

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Veröffentlicht in:	Clinical and experimental pharmacology & physiology 1991-07, Vol.18 (7), p.509-515
Hauptverfasser:	Kohzuki, Masahiro, Johnston, Colin I., Abe, Keishi, Chai, Siew Yeen, Casley, David J., Yasujima, Minoru, Yoshinaga, Kaoru, Mendelsohn, Frederick A. O.
Format:	Artikel
Sprache:	eng
Schlagworte:	adrenal Adrenal Glands - metabolism Adrenal Glands - ultrastructure Animals Autoradiography Biological and medical sciences Cell receptors Cell structures and functions endothelin Endothelins - metabolism Female Fundamental and applied biological sciences. Psychology heart kidney Kidney - metabolism Kidney - ultrastructure Miscellaneous Molecular and cellular biology Myocardium - metabolism Myocardium - ultrastructure Rats Rats, Inbred Strains receptor Receptors, Cell Surface - metabolism Receptors, Cholinergic - metabolism Receptors, Endothelin Receptors, Peptide sarafotoxin Viper Venoms - metabolism
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