Palladium-Catalyzed Asymmetric Allylic Alkylation of α-Aryl Ketones

Quaternary centers can be created asymmetrically in high enantiomeric excess by the proper choice of ligand and metal cation in the Pd‐catalyzed asymmetric allylic alkylation of α‐aryl ketones. A broad range of ketone enolates can be tolerated in the reaction, as illustrated by the synthesis of conf...

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Veröffentlicht in:	Angewandte Chemie International Edition 2002-09, Vol.41 (18), p.3492-3495
Hauptverfasser:	Trost, Barry M., Schroeder, Gretchen M., Kristensen, Jesper
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkylation aryl ketones asymmetric catalysis Catalysis enantioselectivity Ketones - chemistry ligand effects Naphthalenes - chemistry palladium Palladium - chemistry Tetralones
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