Control of locomotor activity in humans and animals in the absence of supraspinal influences
Electrical epidural stimulation of the dorsal surface of the spinal cord at the level of the second lumbar segment induced step-like movements accompanied by the corresponding electromyographic activity in the leg muscles in patients lacking supraspinal influences as a result of vertebral trauma. Tr...
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| Veröffentlicht in: | Neuroscience and behavioral physiology 2002-07, Vol.32 (4), p.417-424 |
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| creator | Gerasimenko, Yu P Makarovskii, A N Nikitin, O A |
| description | Electrical epidural stimulation of the dorsal surface of the spinal cord at the level of the second lumbar segment induced step-like movements accompanied by the corresponding electromyographic activity in the leg muscles in patients lacking supraspinal influences as a result of vertebral trauma. Triggering of stepping movements was shown to occur with particular stimulation parameters. The results provide evidence that in humans, as in other mammals, the spinal cord contains a network of interneurons acting as generators of stepping movements and producing coordinated patterns of movement activity. Experiments on chronic spinal cats demonstrated the leading role of the propriospinal system of the spinal cord inactivating the spinal generators of stepping in response to epidural stimuli. |
| doi_str_mv | 10.1023/A:1015836428932 |
| format | Article |
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Triggering of stepping movements was shown to occur with particular stimulation parameters. The results provide evidence that in humans, as in other mammals, the spinal cord contains a network of interneurons acting as generators of stepping movements and producing coordinated patterns of movement activity. 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Triggering of stepping movements was shown to occur with particular stimulation parameters. The results provide evidence that in humans, as in other mammals, the spinal cord contains a network of interneurons acting as generators of stepping movements and producing coordinated patterns of movement activity. 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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adult Animals Biomechanical Phenomena Brain Stem - physiology Cats Electric Stimulation Electrodes, Implanted Electromyography Electrophysiology Humans Leg - innervation Leg - physiology Motor Activity - physiology Movement - physiology Muscle, Skeletal - innervation Muscle, Skeletal - physiology Spinal Cord - physiology Spinal Cord Injuries - physiopathology |
| title | Control of locomotor activity in humans and animals in the absence of supraspinal influences |
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