Developmental regulation of intracellular and surface androgen receptors in T cells

Increasing information indicates that testosterone actions on cells are mediated not only through the classical intracellular androgen receptor (iAR), but also through membrane androgen receptors (mAR) on cell surfaces. Here, we investigate the expression pattern of mAR and iAR in thymic T cells, wh...

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Veröffentlicht in:	Steroids 2002-10, Vol.67 (11), p.925-931
Hauptverfasser:	Benten, W.Peter M, Becker, Andrea, Schmitt-Wrede, Hans-Peter, Wunderlich, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen receptor Animals Biological and medical sciences Biological Transport - drug effects CD4 Antigens - analysis CD8 Antigens - analysis Cell Membrane - chemistry Cell Nucleus - metabolism Cell receptors Cell structures and functions Cytoplasm - metabolism Female Flow Cytometry Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors Lymphocyte Count Metribolone - metabolism Mice Mice, Inbred C57BL Microscopy, Confocal Molecular and cellular biology Receptors, Androgen - analysis Receptors, Androgen - genetics Receptors, Androgen - metabolism Sex steroids Spleen - cytology Surface receptor T cells T-Lymphocytes - chemistry T-Lymphocytes - drug effects T-Lymphocytes - ultrastructure Testosterone Testosterone - blood Testosterone - pharmacology Thymus Thymus Gland - cytology Thymus Gland - drug effects Thymus Gland - growth & development
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