Bcl‐2‐Mediated Regulation of CD69‐Induced Apoptosis of Human Eosinophils: Identification and Characterization of a Novel Receptor‐Induced Mechanism and Relationship to CD95‐Transduced Signalling

Elimination of the eosinophils from the airways by selective induction of apoptosis represents a therapeutic approach for asthma. Here we report on a possible target molecule, the surface receptor CD69. To simulate an asthmatic response, segmental allergen challenge in mild asthmatics was performed....

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