Human Macrophages Accumulate HIV‐1 Particles in MHC II Compartments

Macrophages are important targets for HIV‐1 infection and harbor the virions in an as yet unidentified organelle. To determine the location of HIV‐1 in these cells, an extensive analysis of primary human macrophages infected in vitro with HIV‐1 was carried out by immuno‐electron microscopy. Virus pa...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2002-10, Vol.3 (10), p.718-729
Hauptverfasser:	Raposo, Graça, Moore, Marilyn, Innes, Donald, Leijendekker, Richtje, Leigh‐Brown, Andrew, Benaroch, Philippe, Geuze, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	budding Cell Compartmentation Histocompatibility Antigens Class II - immunology HIV-1 - immunology HIV-1 - isolation & purification HIV-1 - physiology Humans Macrophages - virology Membrane Fusion MIIC MVB viral assembly
Online-Zugang:	Volltext
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