Effects of Irradiation on Biological Behavior of Carcinoma Cells under Carcinoma-stromal Cell Interaction and Air-liquid Interface: A Possible Model for Testing Radiosensitivity of Carcinoma of the Upper Aerodigestive Tract Using a Collagen Gel Culture System

Carcinoma-stromal cell interaction and air-liquid interface (ALI) constitute a specific microenvironment that modulates the biological behavior of carcinoma cells of the upper aerodigestive tract. Although radiotherapy is a useful tool for treating carcinomas of this organ, effects of irradiation on...

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Veröffentlicht in:	Pathology, research and practice research and practice, 2002, Vol.198 (7), p.469-478
Hauptverfasser:	Matsuyama, Atsuji, Toda, Shuji, Yamada, Shoichiro, Inokuchi, Akira, Sugihara, Hajime
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - pathology Air Air-liquid interface Animals Apoptosis - radiation effects Carcinoma Carcinoma, Squamous Cell - pathology Carcinoma-stromal cell interaction Cell Communication - radiation effects Cell Culture Techniques - methods Cell Division - radiation effects Collagen Fibroblasts - pathology Gels Humans Irradiation Laryngeal Neoplasms - pathology Mouth Neoplasms - pathology Neoplasm Invasiveness Radiation Tolerance Rats Stromal Cells - pathology Time Factors Tumor Cells, Cultured
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