Interferon‐Induced Mx Proteins: Dynamin‐Like GTPases with Antiviral Activity

Mx proteins are interferon‐induced GTPases that belong to the dynamin superfamily of large GTPases. Similarities include a high molecular weight, a propensity to self‐assemble, a relatively low affinity for GTP, and a high intrinsic rate of GTP hydrolysis. A unique property of Mx GTPases is their an...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2002-10, Vol.3 (10), p.710-717
Hauptverfasser:	Haller, Otto, Kochs, Georg
Format:	Artikel
Sprache:	eng
Schlagworte:	antiviral activity Antiviral Agents - physiology Dynamins - physiology GTP Phosphohydrolases - physiology GTP-Binding Proteins - biosynthesis guanylate‐binding protein influenza virus interferon Interferons - physiology intracellular transport La Crosse virus Molecular Weight MxA GTPase Myxovirus Resistance Proteins oligomerization Subcellular Fractions - enzymology Thogoto virus
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