Persistence of antibody and immunologic memory in children immunized with hepatitis B vaccine at birth

Forty-two healthy children immunized with a course of hepatitis B vaccine beginning at birth were tested at 6 years of age for persistence of anti-hepatitis B antibody (anti-HBs) and then given a booster dose of vaccine. Although nearly one-half had become seronegative, all retained robust immunolog...

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Veröffentlicht in:The Pediatric infectious disease journal 2002-08, Vol.21 (8), p.793-795
Hauptverfasser: Seto, Dexter, West, David J, Ioli, Virginia A
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container_title The Pediatric infectious disease journal
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creator Seto, Dexter
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description Forty-two healthy children immunized with a course of hepatitis B vaccine beginning at birth were tested at 6 years of age for persistence of anti-hepatitis B antibody (anti-HBs) and then given a booster dose of vaccine. Although nearly one-half had become seronegative, all retained robust immunologic memory and rapidly regained a protective anti-HBs titer of at least 10 mIU/ml after booster vaccination.
doi_str_mv 10.1097/00006454-200208000-00021
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subjects Antibodies, Viral - blood
Biological and medical sciences
Child
Child, Preschool
Female
Hepatitis B Vaccines - administration & dosage
Hepatitis B Vaccines - immunology
Hepatitis B virus - immunology
Human viral diseases
Humans
Immunization, Secondary
Immunologic Memory
Infant
Infant, Newborn
Infectious diseases
Male
Medical sciences
Time Factors
Vaccination
Viral diseases
Viral hepatitis
title Persistence of antibody and immunologic memory in children immunized with hepatitis B vaccine at birth
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