Persistence of antibody and immunologic memory in children immunized with hepatitis B vaccine at birth
Forty-two healthy children immunized with a course of hepatitis B vaccine beginning at birth were tested at 6 years of age for persistence of anti-hepatitis B antibody (anti-HBs) and then given a booster dose of vaccine. Although nearly one-half had become seronegative, all retained robust immunolog...
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Veröffentlicht in: | The Pediatric infectious disease journal 2002-08, Vol.21 (8), p.793-795 |
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creator | Seto, Dexter West, David J Ioli, Virginia A |
description | Forty-two healthy children immunized with a course of hepatitis B vaccine beginning at birth were tested at 6 years of age for persistence of anti-hepatitis B antibody (anti-HBs) and then given a booster dose of vaccine. Although nearly one-half had become seronegative, all retained robust immunologic memory and rapidly regained a protective anti-HBs titer of at least 10 mIU/ml after booster vaccination. |
doi_str_mv | 10.1097/00006454-200208000-00021 |
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subjects | Antibodies, Viral - blood Biological and medical sciences Child Child, Preschool Female Hepatitis B Vaccines - administration & dosage Hepatitis B Vaccines - immunology Hepatitis B virus - immunology Human viral diseases Humans Immunization, Secondary Immunologic Memory Infant Infant, Newborn Infectious diseases Male Medical sciences Time Factors Vaccination Viral diseases Viral hepatitis |
title | Persistence of antibody and immunologic memory in children immunized with hepatitis B vaccine at birth |
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