A Multicomponent Reaction for the One-Pot Synthesis of 4-Aza-2,3-didehydropodophyllotoxin and Derivatives

A convergent method has been found to prepare 4-aza-2,3-didehydropodophyllotoxin and derivatives in a one-pot procedure. The mechanism of the reaction between tetronic acid, anilines, and benzaldehydes is discussed.

Bibliographische Detailangaben

Veröffentlicht in:	Organic letters 2002-09, Vol.4 (19), p.3187-3189
Hauptverfasser:	Tratrat, Christophe, Giorgi-Renault, Sylviane, Husson, Henri-Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - adverse effects Antineoplastic Agents - chemistry Molecular Structure Podophyllotoxin - analogs & derivatives Podophyllotoxin - chemical synthesis Podophyllotoxin - chemistry
Online-Zugang:	Volltext
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