Norepinephrine and Phenylephrine Effects on Right Ventricular Function in Experimental Canine Pulmonary Embolism

In a canine model of pulmonary embolism (PE) produced by infusion of autologous blood clots, mean arterial blood pressure (MAP) decreased to 73 ± 4 mm Hg while cardiac output (CO) decreased to less than 50 percent of baseline. Intravenous infusion of phenylephrine (PHEN) and norepinephrine (NE) rest...

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Veröffentlicht in:	Chest 1991-09, Vol.100 (3), p.796-801
Hauptverfasser:	Hirsch, Leroy J., Rooney, Michael W., Wat, Samuel S., Kleinmann, Bruce, Mathru, Mali
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Pressure - drug effects Cardiac Output - drug effects Cardiovascular system Dogs Male Medical sciences Myocardium - metabolism Norepinephrine - pharmacology Oxygen Consumption - drug effects Pharmacology. Drug treatments Phenylephrine - pharmacology Pulmonary Embolism - metabolism Pulmonary Embolism - physiopathology Vascular Resistance - drug effects Ventricular Function, Right - drug effects
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