Gene expression and metastasis of somatic cell hybrids between murine fibroblast cell lines of different malignant potential

We have used somatic cell hybrids to study the relationship between ras sensitivity, metastasis, and the expression of ras-responsive or "metastasis-associated" genes. We have previously shown that NIH 3T3 cells are nontumorigenic, but are made metastatic by transfection and expression of...

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Veröffentlicht in:	Somatic cell and molecular genetics 1991-07, Vol.17 (4), p.377-389
Hauptverfasser:	TUCK, A. B, WILSON, S. M, SERGOVICH, F. R, CHAMBERS, A. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Line Chick Embryo Chromosomes Dissemination Fibroblasts - pathology Gene Expression Regulation, Neoplastic Hybrid Cells - pathology Male Medical sciences Mice Mice, Nude Neoplasm Metastasis - genetics Tumor cell Tumor Cells, Cultured Tumors
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