Feline immunodeficiency virus vectors. Gene transfer to mouse retina following intravitreal injection

Background Transduction of the murine retinal pigmented epithelium (RPE) with adenovirus vectors requires technically difficult and invasive subretinal injections. This study tested the hypothesis that recombinant vectors based on feline immunodeficiency virus (FIV) could access the retina following...

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Veröffentlicht in:	The journal of gene medicine 2002-09, Vol.4 (5), p.463-469
Hauptverfasser:	Derksen, Todd A., Sauter, Sybille L., Davidson, Beverly L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cornea Cornea - metabolism Cornea - ultrastructure FIV Gene therapy Gene Transfer Techniques Genetic Vectors - administration & dosage Glucuronidase - deficiency Glucuronidase - genetics Immunodeficiency Virus, Feline Mice Mice, Inbred BALB C MPS Mucopolysaccharidosis VII - therapy Retina - metabolism Retina - ultrastructure trabecular meshwork
Online-Zugang:	Volltext
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