Analysis of two IgM isotypes in Atlantic salmon and brown trout

Atlantic salmon ( Salmo salar) possesses two distinct subpopulations of polymeric IgM which are separable by anion exchange chromatography. Consistent with this finding there are two isotypic IgM heavy chain genes, CμA and CμB, in the genome of this species, presumably as a result of ancestral tetra...

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Veröffentlicht in:	Molecular immunology 2002-10, Vol.39 (5), p.313-321
Hauptverfasser:	Hordvik, Ivar, Berven, Frode S, Solem, Stein Tore, Hatten, Frode, Endresen, Curt
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Chromatography, Ion Exchange Cloning, Molecular Immunoglobulin Immunoglobulin Heavy Chains - analysis Immunoglobulin Heavy Chains - genetics Immunoglobulin Isotypes - genetics Immunoglobulin M - chemistry Immunoglobulin M - classification Immunoglobulin M - genetics Isotype Molecular Sequence Data Salmon Salmon - immunology Tetraploidy Trout Trout - immunology
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