Interleukin-10 promoter polymorphisms in patients with multiple sclerosis

The expression level of interleukin-10 (IL-10) is related to polymorphisms −1082 (G/A), −819 (T/C) and −592 (A/C) in the promoter region of the IL-10 gene. The distribution of these polymorphisms was analyzed to determine whether they could influence disease susceptibility or clinical course in mult...

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Veröffentlicht in:	Journal of the neurological sciences 2002-10, Vol.202 (1), p.93-97
Hauptverfasser:	Myhr, Kjell-Morten, Vågnes, Kari S, Marøy, Tove H, Aarseth, Jan H, Nyland, Harald I, Vedeler, Christian A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Clinical course Disability Disease susceptibility Female Genetic Predisposition to Disease Haplotypes Humans IL-10 promoter polymorphism Interleukin-10 - genetics Male Medical sciences Multiple sclerosis Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Multiple Sclerosis, Chronic Progressive - genetics Multiple Sclerosis, Chronic Progressive - immunology Multiple Sclerosis, Relapsing-Remitting - genetics Multiple Sclerosis, Relapsing-Remitting - immunology Neurology Polymorphism, Genetic Promoter Regions, Genetic
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